vonapanitase
Recombinant proteinexperimental
Clinical trial activity
8 trials · 3 clinical orgs · 0 marketing orgs
Phase 1
5
Phase 2
5
Phase 3
2
Phase 4
0
Earliest trial started Nov 1, 2008 (NCT00679991)
Timeline
Indications
Mechanism of action
- ElastinPROTEOLYTIC ENZYME
ELN proteolytic enzyme
Recombinant human chymotrypsin-like elastase family member 1 (CELA1) shown to cleave the elastin component of elastic fibers.
- PseudolysinSupplementation
lasB supplementation
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3545070 ↗
Also known as
- cbpp protein, human
- cholesterol-binding pancreatic proteinase protein, human
- cholesterol-binding protein
- pancreatic elastase 1 protein, human
- prt-201
- prt-201
- prt-201
- vonapanitase
- vonapanitase
- vonapanitase
- vonapanitase
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02956993 | Phase 1 | Nov 1, 2016 | Proteon Therapeutics |
| NCT02953496 | Phase 1 | Oct 26, 2016 | Proteon Therapeutics |
| NCT02414841 | Phase 3 | Aug 1, 2015 | Proteon Therapeutics |
| NCT02110901 | Phase 3 | Jul 1, 2014 | Proteon Therapeutics |
| NCT01616290 | Phase 1 | Oct 1, 2012 | Department of Veteran Affairs, Proteon Therapeutics, University of California, San Francisco |
| NCT01305824 | Phase 2 | Mar 1, 2011 | Proteon Therapeutics |
| NCT01001351 | Phase 1/Phase 2 (Phase 2) | Sep 1, 2009 | Proteon Therapeutics |
| NCT00679991 | Phase 1/Phase 2 (Phase 2) | Nov 1, 2008 | Proteon Therapeutics |
Showing 8 of 8 trials
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Organizations
Research & Development (3)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Proteon Therapeutics | For profit | 8 | 8 | 3 | 2008 |
| Department of Veteran Affairs | Government | 1 | 0 | 1 | 2012 |
| University of California, San Francisco | Academic/Hospital | 1 | 0 | 1 | 2012 |
3 organizations
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