nb-001
Small moleculeexperimental
Clinical trial activity
5 trials · 22 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
5
Phase 3
3
Phase 4
0
Earliest trial started Feb 1, 2007 (NCT00453401)
Timeline
Indications
Mechanism of action
- Brain adenylate cyclase 1INHIBITOR
ADCY1 inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
Nc1ncnc2c1ncn2CCNCCCCCO- Mol. weight
- 264.33 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4297305 ↗
Also known as
- nb-001
- nb-001
- nb-001
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05290493 | Phase 2 | Feb 10, 2022 | Nobias Therapeutics, Inc. |
| NCT01695187 | Phase 3 | Oct 1, 2012 | BlueWillow Biologics |
| NCT01321359 | Phase 3 | Apr 1, 2011 | BlueWillow Biologics |
| NCT01324466 | Phase 3 | Apr 1, 2011 | BlueWillow Biologics |
| NCT00453401 | Phase 2 | Feb 1, 2007 | Advanced Clinical Research Inc., Advance Healthcare, AMR Advanced Medical Research GmbH, Benchmark Research, BlueWillow Biologics, Bock Clinical Research Incorporated, Clinical Research of West Florida, Coastal Carolina Research, Derm Research Incorporated, Derm Research, PLLC, Front Range Clinical Research, J&S Studies Inc., Medical Affiliated Research Center, Inc., New River Valley Research Institute, Omega Medical Research, Research Across America, Suncoast Clinical Research, Wake Research Associates, Wenatchee Valley Medical Center, Westlake Medical Research, Westover Heights Clinic |
Showing 5 of 5 trials
Page 1 / 1
Organizations
Research & Development (22)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| BlueWillow Biologics | For profit | 4 | 4 | 2 | 2007 |
| Advanced Clinical Research Inc. | For profit | 1 | 0 | 1 | 2007 |
| Advance Healthcare | Academic/Hospital | 1 | 0 | 1 | 2007 |
| AMR Advanced Medical Research GmbH | For profit | 1 | 0 | 1 | 2007 |
| Benchmark Research | For profit | 1 | 0 | 1 | 2007 |
| Bock Clinical Research Incorporated | Academic/Hospital | 1 | 0 | 1 | 2007 |
| Clinical Research of West Florida | For profit | 1 | 0 | 1 | 2007 |
| Coastal Carolina Research | For profit | 1 | 0 | 1 | 2007 |
| Derm Research Incorporated | For profit | 1 | 0 | 1 | 2007 |
| Derm Research, PLLC | For profit | 1 | 0 | 1 | 2007 |
| Front Range Clinical Research | For profit | 1 | 0 | 1 | 2007 |
| J&S Studies Inc. | For profit | 1 | 0 | 1 | 2007 |
| Medical Affiliated Research Center, Inc. | For profit | 1 | 0 | 1 | 2007 |
| New River Valley Research Institute | Academic/Hospital | 1 | 0 | 1 | 2007 |
| Nobias Therapeutics, Inc. | For profit | 1 | 1 | 1 | 2022 |
| Omega Medical Research | For profit | 1 | 0 | 1 | 2007 |
| Research Across America | For profit | 1 | 0 | 1 | 2007 |
| Suncoast Clinical Research | For profit | 1 | 0 | 1 | 2007 |
| Wake Research Associates | For profit | 1 | 0 | 1 | 2007 |
| Wenatchee Valley Medical Center | Academic/Hospital | 1 | 0 | 1 | 2007 |
22 organizations
Page 1 / 2