vapendavir
Small moleculeexperimental
Clinical trial activity
9 trials · 3 clinical orgs · 0 marketing orgs
Phase 1
5
Phase 2
5
Phase 3
0
Phase 4
0
Earliest trial started Aug 1, 2010 (NCT01175226)
Timeline
Indications
Studied for
- Asthma · Phase 2
- Enterovirus · Phase 2
- Enterovirus Infections · Phase 2
- Healthy Volunteers · Phase 1/Phase 2
- Infections · Phase 2
- Lung Diseases · Phase 2
- Lung Diseases, Obstructive · Phase 2
- Pulmonary Disease, Chronic Obstructive · Phase 2
- Respiratory Tract Diseases · Phase 2
- Respiratory Tract Infections · Phase 2
- Rhinovirus · Phase 2
- RNA Virus Infections · Phase 2
- Virus Diseases · Phase 2
Mechanism of action
- Human rhinovirus sp.INHIBITOR
Human rhinovirus sp. inhibitor
- VP1 capsid proteinINHIBITOR
VP1 capsid protein inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
CCOc1noc2cc(OCCC3CCN(c4ccc(C)nn4)CC3)ccc12- Mol. weight
- 382.46 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL2062774 ↗
Also known as
- bta798
- bta798
- vapendavir
- vapendavir
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06834295 | Phase 1/Phase 2 (Phase 2) | Mar 12, 2025 | Altesa Biosciences, Inc. |
| NCT06149494 | Phase 2 | Nov 20, 2023 | Altesa Biosciences, Inc. |
| NCT05962645 | Phase 1 | May 19, 2023 | Altesa Biosciences, Inc. |
| NCT03024177 | Phase 2 | Jan 12, 2017 | Aviragen Therapeutics |
| NCT02877264 | Phase 1 | Jun 1, 2016 | Aviragen Therapeutics |
| NCT02367313 | Phase 2 | Feb 1, 2015 | Aviragen Therapeutics |
| NCT02204501 | Phase 1 | May 1, 2014 | Aviragen Therapeutics, Prism Research |
| NCT02101866 | Phase 1 | Mar 1, 2014 | Aviragen Therapeutics, Prism Research |
| NCT01175226 | Phase 2 | Aug 1, 2010 | Aviragen Therapeutics |
Showing 9 of 9 trials
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Organizations
Research & Development (3)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Aviragen Therapeutics | For profit | 6 | 6 | 2 | 2010 |
| Altesa Biosciences, Inc. | For profit | 3 | 3 | 2 | 2023 |
| Prism Research | For profit | 2 | 0 | 1 | 2014 |
3 organizations
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