smallpox vaccine, heat-stable freeze-dried powder, first generation

Vaccineapproved

Approved

Jul 1, 1955

Clinical trial activity

9 trials · 4 clinical orgs · 0 marketing orgs

Phase 1
4
Phase 2
6
Phase 3
0
Phase 4
0

Earliest trial started Nov 12, 2001 (NCT00026611)

Timeline

1950s

  1. Jul 1, 1955

    Earliest FDA Approval

2000s

  1. Jan 1, 2001

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2002

    Earliest Phase 1 Sponsor(trial)

Indications

Mechanism of action

Approval history

  • approvedJul 1, 1955

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Also known as

  • dryvax
  • dryvax
  • smallpox vaccine, heat-stable freeze-dried powder, first generation

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05762523Phase 1May 18, 2019Government of Russia
NCT00437021Phase 1/Phase 2 (Phase 2)Apr 1, 2007National Institute of Allergy and Infectious Diseases (NIAID)
NCT00032708Phase 2Apr 1, 2004National Institute of Allergy and Infectious Diseases (NIAID)
NCT00068198Phase 1Sep 9, 2003National Institute of Allergy and Infectious Diseases (NIAID)
NCT00053495Phase 2Jan 1, 2003Sanofi
NCT00053482Phase 2Jan 1, 2003Sanofi
NCT00053508Phase 2Sep 1, 2002Sanofi
NCT00042094Phase 1Mar 1, 2002DynPort Vaccine Company LLC
NCT00026611Phase 2Nov 12, 2001National Institute of Allergy and Infectious Diseases (NIAID)
Showing 9 of 9 trials
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Organizations

Research & Development (4)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
National Institute of Allergy and Infectious Diseases (NIAID)Government4422001
SanofiFor profit3312002
DynPort Vaccine Company LLCFor profit1112002
Government of RussiaGovernment1112019
4 organizations
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