anti-ny eso-1 tcr-transduced t cells
Cell therapyexperimental
Clinical trial activity
7 trials · 11 clinical orgs · 0 marketing orgs
Phase 1
6
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Apr 1, 2015 (NCT02457650)
Timeline
2010s
- Jan 1, 2015
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
- Breast Neoplasms · Phase 1
- Esophageal Neoplasms · Phase 1
- Liposarcoma · Phase 1
- Lung Neoplasms · Phase 1
- Melanoma · Phase 1
- Multiple Myeloma · Phase 1/Phase 2
- Neoplasms · Phase 1
- Neuroblastoma · Phase 1
- Ovarian Neoplasms · Phase 1
- Sarcoma · Phase 1
- Sarcoma, Synovial · Phase 1
- Small Cell Lung Carcinoma · Phase 1
- Urinary Bladder Neoplasms · Phase 1
Mechanism of action
- Tumor antigensImmunity, passive
immunity, passive - tumor antigen
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- anti-ny eso-1 tcr-transduced t cells
- anti-ny-eso-1 tcr transduced t cells
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06942143 | Phase 1 | May 22, 2025 | Guangzhou FineImmune Biotechnology Co., LTD., Sun Yat-Sen University |
| NCT06889766 | Phase 1 | Mar 24, 2025 | University of Lausanne |
| NCT06083883 | Phase 1 | Feb 1, 2024 | University of Texas at Houston |
| NCT06066359 | Phase 1/Phase 2 (Phase 2) | Nov 30, 2023 | University of Texas at Houston |
| NCT05620693 | N/A | Nov 11, 2022 | Shenzhen University |
| NCT03029273 | Phase 1 | Mar 1, 2017 | Guangdong Xiangxue Precision Medical Technology Co., Ltd, Guangzhou Medical University, Guangzhou Xiangxue Pharmaceutical Co., Ltd, Xiangxue Life Science Research Center |
| NCT02457650 | Phase 1 | Apr 1, 2015 | China Medical University, Shenzhen Institute for Innovation and Translational Medicine |
Showing 7 of 7 trials
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Organizations
Research & Development (11)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Texas at Houston | Academic/Hospital | 2 | 2 | 2 | 2023 |
| China Medical University | Academic/Hospital | 1 | 1 | 1 | 2015 |
| Guangdong Xiangxue Precision Medical Technology Co., Ltd | For profit | 1 | 0 | 1 | 2017 |
| Guangzhou FineImmune Biotechnology Co., LTD. | Government | 1 | 1 | 1 | 2025 |
| Guangzhou Medical University | Academic/Hospital | 1 | 1 | 1 | 2017 |
| Guangzhou Xiangxue Pharmaceutical Co., Ltd | For profit | 1 | 0 | 1 | 2017 |
| Shenzhen Institute for Innovation and Translational Medicine | Academic/Hospital | 1 | 0 | 1 | 2015 |
| Shenzhen University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Sun Yat-Sen University | Academic/Hospital | 1 | 0 | 1 | 2025 |
| University of Lausanne | Academic/Hospital | 1 | 1 | 1 | 2025 |
| Xiangxue Life Science Research Center | Academic/Hospital | 1 | 0 | 1 | 2017 |
11 organizations
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