tsr-022
mAbexperimental
Clinical trial activity
7 trials · 5 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
4
Phase 3
1
Phase 4
0
Earliest trial started Jul 1, 2016 (NCT02817633)
Timeline
Indications
Studied for
- Carcinoma, Hepatocellular · Phase 1/Phase 2
- Carcinoma, Non-Small-Cell Lung · Phase 2/Phase 3
- Diffuse Intrinsic Pontine Glioma · Phase 1/Phase 2
- Ependymoma · Phase 1/Phase 2
- Glioblastoma · Phase 1/Phase 2
- Glioma · Phase 1/Phase 2
- Hepatoblastoma · Phase 1/Phase 2
- Hodgkin Disease · Phase 1/Phase 2
- Liver Neoplasms · Phase 2
- Melanoma · Phase 2
- Neoplasms · Phase 1
- Osteosarcoma · Phase 1/Phase 2
- Rhabdomyosarcoma · Phase 1/Phase 2
- Small Cell Lung Carcinoma · Phase 1
- Uterine Cervical Neoplasms · Phase 2
Mechanism of action
Hepatitis A virus cellular receptor 2 inhibitor
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4298123 ↗
Also known as
- tsr-022
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06521567 | Phase 1/Phase 2 (Phase 2) | Sep 13, 2024 | GlaxoSmithKline |
| NCT06238635 | Phase 2 | Mar 11, 2024 | GlaxoSmithKline, Harvard University |
| NCT04655976 | Phase 2/Phase 3 (Phase 3) | Dec 8, 2020 | GlaxoSmithKline |
| NCT04139902 | Phase 2 | Dec 15, 2019 | Tesaro, University of Pittsburgh |
| NCT03680508 | Phase 2 | Oct 31, 2018 | University of Hawaii |
| NCT03307785 | Phase 1 | Oct 12, 2017 | Tesaro |
| NCT02817633 | Phase 1 | Jul 1, 2016 | Tesaro |
Showing 7 of 7 trials
Page 1 / 1
Organizations
Research & Development (5)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| GlaxoSmithKline | For profit | 3 | 2 | 2 | 2020 |
| Tesaro | For profit | 3 | 2 | 2 | 2016 |
| Harvard University | Academic/Hospital | 1 | 1 | 1 | 2024 |
| University of Hawaii | Academic/Hospital | 1 | 1 | 1 | 2018 |
| University of Pittsburgh | Academic/Hospital | 1 | 1 | 1 | 2019 |
5 organizations
Page 1 / 1