anti cd45 monoclonal antibody
mAbexperimental
Clinical trial activity
10 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
10
Phase 2
4
Phase 3
0
Phase 4
0
Earliest trial started Jul 1, 2001 (NCT00590460)
Timeline
2000s
- Jan 1, 2001
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
- Anemia, Aplastic · Phase 1/Phase 2
- Deficiency Diseases · Phase 1/Phase 2
- Epstein-Barr Virus Infections · Phase 1
- Fanconi Anemia · Phase 1/Phase 2
- Hematologic Neoplasms · Phase 1/Phase 2
- Leukemia · Phase 1
- Lymphoma · Phase 1
- Metabolic Diseases · Phase 1/Phase 2
- Nasopharyngeal Carcinoma · Phase 1
- Nasopharyngeal Neoplasms · Phase 1
- Primary Immunodeficiency Diseases · Phase 1/Phase 2
- Wiskott-Aldrich Syndrome · Phase 1/Phase 2
Mechanism of action
- Leukocyte common antigenINHIBITOR
PTPRC inhibitor
Chemistry & pharmacology
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Also known as
- anti-cd45
- anti cd45 monoclonal antibody
- cd45 antibodies
- cd45 mab
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00706316 | Phase 1 | Dec 1, 2007 | University of Toronto |
| NCT00579137 | Phase 1/Phase 2 (Phase 2) | Oct 1, 2007 | Baylor University |
| NCT00515957 | Phase 1 | Aug 1, 2007 | Baylor University, Methodist Cancer Center, Houston, Texas |
| NCT00082225 | Phase 1 | Oct 1, 2003 | Baylor University, Methodist Cancer Center, Houston, Texas |
| NCT00078546 | Phase 1 | Sep 1, 2003 | Baylor University, Methodist Cancer Center, Houston, Texas |
| NCT00057005 | Phase 1 | Feb 1, 2003 | Baylor University, Methodist Cancer Center, Houston, Texas |
| NCT00056966 | Phase 1/Phase 2 (Phase 2) | Nov 1, 2002 | Baylor University, Methodist Cancer Center, Houston, Texas |
| NCT00056979 | Phase 1/Phase 2 (Phase 2) | Jun 1, 2002 | Baylor University, Methodist Cancer Center, Houston, Texas |
| NCT00586274 | Phase 1 | Mar 1, 2002 | Baylor University, The University of Texas, Dallas |
| NCT00590460 | Phase 1/Phase 2 (Phase 2) | Jul 1, 2001 | Baylor University, Methodist Cancer Center, Houston, Texas |
Showing 10 of 10 trials
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Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Baylor University | Academic/Hospital | 9 | 9 | 2 | 2001 |
| Methodist Cancer Center, Houston, Texas | Academic/Hospital | 7 | 0 | 2 | 2001 |
| The University of Texas, Dallas | Academic/Hospital | 1 | 0 | 1 | 2002 |
| University of Toronto | Academic/Hospital | 1 | 1 | 1 | 2007 |
4 organizations
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