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taurine

Small moleculeexperimental

Taurine is a naturally occurring organic compound with the chemical formula C2H7NO3S, and is a non-proteinogenic amino sulfonic acid widely distributed in mammalian tissues and organs. Structurally, by containing a sulfonic acid group instead of a carboxylic acid group, it is not involved in protein synthesis but is still usually referred to as an amino acid. As non-proteinogenic amino sulfonic acid, it is not encoded by the genetic code and is distinguished from the protein-building α-amino acids. — Wikipedia

Clinical trial activity

34 trials · 46 clinical orgs · 0 marketing orgs

Phase 1
5
Phase 2
8
Phase 3
4
Phase 4
4

Earliest trial started Apr 1, 2005 (NCT00217165)

Timeline

2000s

  1. Jan 1, 2005

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2006

    Earliest Phase 1 Sponsor(trial)

2010s

  1. Jan 1, 2012

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

  • taurineSupplementation

    taurine supplementation

Chemistry & pharmacology

Loading structure…

SMILES

NCCS(=O)(=O)O
Mol. weight
125.15 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 2-aminoethanesulfonic acid
  • aminoethylsulfonic acid
  • aminoethylsulfonic acid
  • aminoethylsulfonic acid
  • o-due
  • o-due
  • taurine
  • taurine
  • taurine
  • taurine
  • taurine
  • taurine
  • taurine
  • taurine
  • taurine hydrochloride
  • taurine monopotassium
  • taurineold
  • taurineold
  • taurine potassium

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07312409N/AApr 1, 2026York University
NCT07263607Phase 2Jan 1, 2026Capital Medical University, Chongqing Medical University, Inner Mongolia Medical University, Kunming Medical University, LanZhou University, North Sichuan Medical University, People's Hospital of Leshan, People's Liberation Army of China, Shandong Provincial Hospital, Sichuan University
NCT07144033N/AJan 1, 2026Chinese University of Hong Kong
NCT07029178Phase 2Nov 24, 2025Jiao Tong University
NCT07212803Phase 4Nov 1, 2025University of the Pacific
NCT06721949Phase 2/Phase 3 (Phase 3)Feb 28, 2025Canadian Institutes of Health Research (CIHR), University of Alberta, University of Toronto
NCT06884566N/AJan 7, 2025University of Central Lancashire
NCT06824571N/ADec 1, 2024Xi'an Medical University
NCT06613542N/ASep 25, 2024Ludwig Maximilians University, Rutgers University, Stanford University, Technical University of Munich, Universitaet Innsbruck
NCT06128252N/AOct 1, 2023People's Liberation Army of China, Xijing Hospital
NCT06123455Phase 2Aug 1, 2023People's Liberation Army of China, Xijing Hospital
NCT06639711Phase 1/Phase 2 (Phase 2)Jul 10, 2023University Of Anbar
NCT05415176N/AJan 1, 2023University of Sao Paulo
NCT05437952N/AJul 31, 2022Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Fundação de Amparo à Pesquisa do Estado de São Paulo, University of Sao Paulo
NCT04772508N/ADec 1, 2020Maharishi Markandeshwar University
NCT04291352N/AJun 1, 2020University of Toronto
NCT05149716N/AJan 13, 2020Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Fundação de Amparo à Pesquisa do Estado de São Paulo, University of Sao Paulo
NCT04218513Phase 1May 7, 2019Nanjing Yoko Biomedical Co., Ltd.
NCT04279600N/AMay 1, 2017Fundação de Amparo à Pesquisa do Estado de São Paulo, University of Sao Paulo
NCT03410537N/AJan 31, 2017People's Liberation Army of China
Showing 20 of 34 trials
Page 1 / 2

Organizations

Research & Development (46)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
People's Liberation Army of ChinaGovernment6532012
University of Sao PauloAcademic/Hospital4412017
Fundação de Amparo à Pesquisa do Estado de São PauloAcademic/Hospital3012017
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Government2012020
Mclean HospitalAcademic/Hospital2122005
Stanley Medical Research InstituteAcademic/Hospital2022006
University of TorontoAcademic/Hospital2122020
Xijing HospitalAcademic/Hospital2022023
Ain Shams UniversityAcademic/Hospital1112015
Canadian Institutes of Health Research (CIHR)Academic/Hospital1012025
Capital Medical UniversityAcademic/Hospital1012026
Chinese University of Hong KongAcademic/Hospital1112026
Chongqing Medical UniversityAcademic/Hospital1012026
Daewoong Pharmaceutical Co. LTD.For profit1112014
Hamad Medical CorporationFor profit1112012
Harvard UniversityAcademic/Hospital1112006
Inner Mongolia Medical UniversityAcademic/Hospital1012026
Jiao Tong UniversityAcademic/Hospital1112025
Kunming Medical UniversityAcademic/Hospital1012026
LanZhou UniversityAcademic/Hospital1012026
46 organizations
Page 1 / 3