ammonia

Small moleculeexperimental

[13N]Ammonia ([13N]NH3) is a useful 13N-labeled compound that has been developed as a positron emission tomography (PET) imaging agent for assessing regional blood flow in tissues. It is indicated for diagnostic PET imaging of the myocardium under rest or pharmacologic stress conditions to evaluate myocardial perfusion in patients with suspected or existing coronary artery disease. No adverse reactions have been reported for Ammonia N 13 Injection based on a review of the published literature, publicly available reference sources, and adverse drug reaction reporting systems. The possibility of interactions of Ammonia N 13 Injection with other drugs taken by patients undergoing PET imaging has not been studied. — NCATS

Clinical trial activity

4 trials · 4 clinical orgs · 0 marketing orgs

Phase 1
2
Phase 2
0
Phase 3
0
Phase 4
0

Earliest trial started Jun 1, 2013 (NCT02015195)

Timeline

2010s

  1. Jan 1, 2015

    Earliest Phase 1 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

[13NH3]
Mol. weight
16.02956 g/mol
Lipinski Ro5
Pass
Rule of 3
Yes
Chirality
Achiral Molecule
Inorganic
No
Polymer
No
Delivery
Parenteral
Availability
Prescription Only

Oral

No

Parenteral

Yes

Topical

No

Sources

Also known as

  • ammonia
  • ammonia
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  • ammonia solution, strong
  • ammonia spirit, aromatic
  • ammonia water
  • ammonia water
  • aromatic ammonia spirit

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05868798Phase 1Oct 1, 2020Charles University
NCT04585672N/AAug 19, 2020Aarhus University
NCT02669563Early Phase 1 (Phase 1)Dec 1, 2015University of Michigan
NCT02015195N/AJun 1, 2013Stanford University
Showing 4 of 4 trials
Page 1 / 1

Organizations

Research & Development (4)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Aarhus UniversityAcademic/Hospital1112020
Charles UniversityAcademic/Hospital1112020
Stanford UniversityAcademic/Hospital1112013
University of MichiganAcademic/Hospital1112015
4 organizations
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