sp-420

Small moleculeexperimental

Clinical trial activity

4 trials · 6 clinical orgs · 0 marketing orgs

Phase 1
2
Phase 2
2
Phase 3
0
Phase 4
0

Earliest trial started Oct 1, 2014 (NCT02274233)

Timeline

2010s

  1. Jan 1, 2014

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2019

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

  • IronCHELATING AGENT

    Iron chelating agent

  • IronSEQUESTERING AGENT

    Iron sequestering agent

Chemistry & pharmacology

Loading structure…

SMILES

COCCOCCOc1ccc(C2=N[C@@](C)(C(=O)O)CS2)c(O)c1
Mol. weight
355.41 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • sp-420
  • sp-420

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05693909Phase 2Sep 4, 2023ICON, Pharmacosmos
NCT04741542Phase 1Mar 9, 2021Abfero Pharmaceuticals, Inc, University of Texas, San Antonio
NCT03801889Phase 2May 31, 2019Abfero Pharmaceuticals, Inc, American University of Beirut
NCT02274233Phase 1Oct 1, 2014Sideris Pharmaceuticals
Showing 4 of 4 trials
Page 1 / 1

Organizations

Research & Development (6)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Abfero Pharmaceuticals, IncFor profit2122019
American University of BeirutAcademic/Hospital1012019
ICONFor profit1012023
PharmacosmosFor profit1112023
Sideris PharmaceuticalsFor profit1112014
University of Texas, San AntonioAcademic/Hospital1112021
6 organizations
Page 1 / 1