sirtuin

Small moleculeexperimental

Sirtuins are a family of signaling proteins involved in metabolic regulation. They are ancient in animal evolution and appear to possess a highly conserved structure throughout all kingdoms of life. Chemically, sirtuins are a class of proteins that possess either mono-ADP-ribosyltransferase or deacylase activity, including deacetylase, desuccinylase, demalonylase, demyristoylase and depalmitoylase activity. The name Sir2 comes from the yeast gene 'silent mating-type information regulation 2', the gene responsible for cellular regulation in yeast. — Wikipedia

Clinical trial activity

1 trials · 4 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Earliest trial started Jul 1, 2015 (NCT02961829)

Timeline

No events for the selected filters.

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • sirtuin
  • sirtuin

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02961829N/AJul 1, 2015Conselho Nacional de Desenvolvimento Científico e Tecnológico, Fundação de Amparo à Pesquisa do Estado de São Paulo, University of Sao Paulo, ViiV Healthcare
Showing 1 of 1 trials
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Organizations

Research & Development (4)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Conselho Nacional de Desenvolvimento Científico e TecnológicoGovernment1012015
Fundação de Amparo à Pesquisa do Estado de São PauloAcademic/Hospital1012015
University of Sao PauloAcademic/Hospital1112015
ViiV HealthcareFor profit1012015
4 organizations
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