sialic acid
Small moleculeexperimental
Sialic acids are a class of alpha-keto acid sugars with a nine-carbon backbone. The term "sialic acid" was first introduced by Swedish biochemist Gunnar Blix in 1952. The most common member of this group is N-acetylneuraminic acid found in animals and some prokaryotes. — Wikipedia
Clinical trial activity
6 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
5
Phase 3
2
Phase 4
0
Earliest trial started Jul 1, 2011 (NCT01359319)
Timeline
Indications
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Loading structure…
SMILES
CC(=O)N[C@H]1[C@H]([C@@H](O)[C@@H](O)CO)O[C@@](O)(C(=O)O)C[C@@H]1O- Mol. weight
- 309.27 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaSialic acid ↗
- ChEMBLCHEMBL152452 ↗
Also known as
- sialic acid
- sialic acid
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05239663 | Phase 3 | Feb 8, 2022 | Sun Yat-Sen University |
| NCT02845609 | Phase 2 | Sep 1, 2016 | Hebrew University |
| NCT02377921 | Phase 3 | May 1, 2015 | Ultragenyx Inc. |
| NCT01830972 | Phase 2 | Jun 1, 2013 | Ultragenyx Inc. |
| NCT01517880 | Phase 2 | May 1, 2012 | Hebrew University, New York University, Ultragenyx Inc., University of California, Los Angeles, Washington University in St. Louis |
| NCT01359319 | Phase 1 | Jul 1, 2011 | Ultragenyx Inc. |
Showing 6 of 6 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Ultragenyx Inc. | For profit | 4 | 4 | 3 | 2011 |
| Hebrew University | Academic/Hospital | 2 | 1 | 1 | 2012 |
| New York University | Academic/Hospital | 1 | 0 | 1 | 2012 |
| Sun Yat-Sen University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| University of California, Los Angeles | Academic/Hospital | 1 | 0 | 1 | 2012 |
| Washington University in St. Louis | Academic/Hospital | 1 | 0 | 1 | 2012 |
6 organizations
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