sevirumab
mAbexperimental
Sevirumab (MSL-109) is a human monoclonal antibody for the treatment of infections with cytomegalovirus in patients with AIDS. — Wikipedia
Clinical trial activity
6 trials · 5 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
3
Phase 3
1
Phase 4
0
Earliest trial started Feb 1, 1995 (NCT00004642)
Timeline
Indications
Mechanism of action
- Envelope glycoprotein HINHIBITOR
gH inhibitor
- CytomegalovirusINHIBITOR
Cytomegalovirus inhibitor
- CytomegalovirusImmunity, passive
Cytomegalovirus immunity, passive
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaSevirumab ↗
- ChEMBLCHEMBL2108881 ↗
Also known as
- ev2-7
- ev2 7 compound
- ev2-7 compound
- msl 109
- msl-109
- msl-109
- msl-109
- protovir
- protovir
- sdz msl 109
- sdz msl 109
- sdz msl-109
- sdz-msl-109
- sevirumab
- sevirumab
- sevirumab
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00000836 | Phase 2 | Nov 2, 1999 | National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT00001061 | Phase 2 | Nov 2, 1999 | Facet Biotech, National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT00002016 | Phase 1 | Nov 2, 1999 | Sandoz |
| NCT00002268 | Phase 1 | Nov 2, 1999 | Sandoz |
| NCT00000135 | Phase 2/Phase 3 (Phase 3) | Sep 1, 1995 | Johns Hopkins University |
| NCT00004642 | Phase 1/Phase 2 (Phase 2) | Feb 1, 1995 | National Center for Research Resources (NCRR), National Institute of Allergy and Infectious Diseases (NIAID) |
Showing 6 of 6 trials
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Organizations
Research & Development (5)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Institute of Allergy and Infectious Diseases (NIAID) | Government | 3 | 2 | 1 | 1995 |
| Sandoz | For profit | 2 | 2 | 1 | 1999 |
| Facet Biotech | For profit | 1 | 0 | 1 | 1999 |
| Johns Hopkins University | Academic/Hospital | 1 | 1 | 1 | 1995 |
| National Center for Research Resources (NCRR) | Government | 1 | 1 | 1 | 1995 |
5 organizations
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