Acoziborole
Small moleculeexperimental
Clinical trial activity
7 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
1
Phase 3
4
Phase 4
0
Earliest trial started Feb 1, 2012 (NCT01533961)
Timeline
Indications
Mechanism of action
Cleavage and polyadenylation specificity factor subunit inhibitor
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Loading structure…
SMILES
CC1(C)OB(O)c2cc(NC(=O)c3ccc(F)cc3C(F)(F)F)ccc21- Mol. weight
- 367.11 g/mol
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL2347704 ↗
Also known as
- scyx7158
- scyx 7158
- scyx-7158
- scyx-7158
- scyx-7158
- scyx-7158
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06356974 | Phase 3 | Apr 8, 2024 | Drugs for Neglected Diseases Initiative, Government of Congo, Government of France, Government of the Democratic Republic of the Congo, Institute of Tropical Medicine, Belgium |
| NCT05947604 | Phase 1 | Feb 9, 2023 | Drugs for Neglected Diseases Initiative |
| NCT05433350 | Phase 2/Phase 3 (Phase 3) | Jul 15, 2022 | Drugs for Neglected Diseases Initiative, Government of the Democratic Republic of the Congo |
| NCT05256017 | Phase 2/Phase 3 (Phase 3) | Dec 30, 2021 | Drugs for Neglected Diseases Initiative, Government of the Democratic Republic of the Congo |
| NCT04270981 | Phase 1 | Feb 10, 2020 | Drugs for Neglected Diseases Initiative, Quotient |
| NCT03087955 | Phase 2/Phase 3 (Phase 3) | Oct 11, 2016 | Drugs for Neglected Diseases Initiative |
| NCT01533961 | Phase 1 | Feb 1, 2012 | Drugs for Neglected Diseases Initiative |
Showing 7 of 7 trials
Page 1 / 1
Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Drugs for Neglected Diseases Initiative | Academic/Hospital | 7 | 7 | 2 | 2012 |
| Government of the Democratic Republic of the Congo | Government | 3 | 0 | 1 | 2021 |
| Government of Congo | Government | 1 | 0 | 1 | 2024 |
| Government of France | Government | 1 | 0 | 1 | 2024 |
| Institute of Tropical Medicine, Belgium | Academic/Hospital | 1 | 0 | 1 | 2024 |
| Quotient | For profit | 1 | 0 | 1 | 2020 |
6 organizations
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