squaric acid dibutylester
Small moleculeexperimental
Clinical trial activity
6 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
4
Phase 2
2
Phase 3
1
Phase 4
0
Earliest trial started Dec 1, 2016 (NCT02965781)
Timeline
Indications
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Loading structure…
SMILES
CCCCOc1c(OCCCC)c(=O)c1=O- Mol. weight
- 226.27 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL2435707 ↗
Also known as
- 3,4-dibutoxy-3-cyclobutene-1,2-dione
- sadbe
- squaric acid dibutylester
- squaric acid dibutylester
- squaric acid dibutyl ester
- squaric acid dibutyl ester
- squaric acid dibutyl ester
- squaric acid dibutyl ester
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05535738 | Phase 2/Phase 3 (Phase 3) | Sep 15, 2022 | University of Massachusetts |
| NCT05414266 | Early Phase 1 (Phase 1) | Aug 15, 2022 | University of Texas at Houston |
| NCT04999631 | Early Phase 1 (Phase 1) | Jan 1, 2022 | Harvard University |
| NCT03521479 | Phase 2 | Mar 12, 2018 | Squarex, LLC |
| NCT03661541 | Phase 1 | Mar 2, 2017 | Squarex, LLC |
| NCT02965781 | Phase 1/Phase 2 (Phase 2) | Dec 1, 2016 | Squarex, LLC |
Showing 6 of 6 trials
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Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Squarex, LLC | For profit | 3 | 3 | 2 | 2016 |
| Harvard University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| University of Massachusetts | Academic/Hospital | 1 | 1 | 1 | 2022 |
| University of Texas at Houston | Academic/Hospital | 1 | 1 | 1 | 2022 |
4 organizations
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