juvista
Recombinant proteinexperimental
Transforming growth factor beta-3 is a protein that in humans is encoded by the TGFB3 gene. — Wikipedia
Clinical trial activity
21 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
10
Phase 2
18
Phase 3
1
Phase 4
0
Earliest trial started May 1, 2001 (NCT00978302)
Timeline
Indications
Mechanism of action
- Transforming growth factor beta-3Supplementation
TGFB3 supplementation
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaTransforming growth factor, beta 3 ↗
- ChEMBLCHEMBL2108833 ↗
Also known as
- avotermin
- avotermin
- avotermin
- avotermin
- juvista
- recombinant human transforming growth factor beta3
- rn1001
- tgfb3 protein, human
- transforming growth factor beta3, human
- transforming growth factor, beta 3 protein, human
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01029158 | Phase 1 | Aug 1, 2009 | RenovoRx |
| NCT00836147 | Phase 1/Phase 2 (Phase 2) | Feb 1, 2009 | Body Aesthetic Plastic Surgery and Skincare Center, St Louis, Missori, RenovoRx |
| NCT00821457 | N/A | Jan 1, 2009 | RenovoRx |
| NCT00742443 | Phase 3 | Dec 1, 2008 | RenovoRx, University of Manchester |
| NCT00710333 | Phase 1/Phase 2 (Phase 2) | Jul 1, 2008 | Body Aesthetic Plastic Surgery and Skincare Center, St Louis, Missori, RenovoRx |
| NCT00469235 | Phase 1/Phase 2 (Phase 2) | Jun 1, 2007 | Body Aesthetic Plastic Surgery and Skincare Center, St Louis, Missori, RenovoRx |
| NCT00430326 | Phase 2 | Nov 1, 2006 | ICON, RenovoRx, University of Hull |
| NCT00432328 | Phase 2 | Oct 1, 2006 | Queen Victoria Hospital, East Grinstead, RenovoRx |
| NCT00629811 | Phase 2 | Sep 1, 2006 | RenovoRx |
| NCT00627536 | Phase 2 | Jul 1, 2006 | RenovoRx |
| NCT00432211 | Phase 2 | May 1, 2006 | RenovoRx, University of Manchester |
| NCT00436449 | Phase 2 | Dec 1, 2004 | RenovoRx, University of Manchester |
| NCT00656227 | Phase 2 | Apr 1, 2004 | RenovoRx |
| NCT00984503 | Phase 2 | Oct 1, 2003 | RenovoRx |
| NCT00594581 | Phase 2 | Oct 1, 2003 | RenovoRx |
| NCT00984581 | Phase 1/Phase 2 (Phase 2) | Apr 1, 2003 | RenovoRx |
| NCT00847795 | Phase 1/Phase 2 (Phase 2) | Sep 1, 2002 | RenovoRx |
| NCT00977951 | Phase 1/Phase 2 (Phase 2) | Sep 1, 2002 | RenovoRx |
| NCT00978367 | Phase 1/Phase 2 (Phase 2) | Feb 1, 2002 | RenovoRx |
| NCT00847925 | Phase 1/Phase 2 (Phase 2) | Nov 1, 2001 | RenovoRx |
Showing 20 of 21 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| RenovoRx | For profit | 21 | 21 | 4 | 2001 |
| Body Aesthetic Plastic Surgery and Skincare Center, St Louis, Missori | Academic/Hospital | 3 | 0 | 1 | 2007 |
| University of Manchester | Academic/Hospital | 3 | 0 | 2 | 2004 |
| ICON | For profit | 1 | 0 | 1 | 2006 |
| Queen Victoria Hospital, East Grinstead | Academic/Hospital | 1 | 0 | 1 | 2006 |
| University of Hull | Academic/Hospital | 1 | 0 | 1 | 2006 |
6 organizations
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