Telitacicept
Recombinant proteinexperimental
Clinical trial activity
49 trials · 37 clinical orgs · 0 marketing orgs
Phase 1
5
Phase 2
32
Phase 3
15
Phase 4
9
Earliest trial started Oct 1, 2015 (NCT02882087)
Timeline
Indications
Approved for
Studied for
- Antibodies, Antineutrophil Cytoplasmic · Phase 1/Phase 2
- Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis · Phase 4
- Anti-N-Methyl-D-Aspartate Receptor Encephalitis · Phase 2
- Antiphospholipid Syndrome · Phase 2
- Arthritis, Rheumatoid · Phase 4
- Connective Tissue Diseases · Phase 2
- Drug Therapy · Phase 3
- Glomerulonephritis, IGA · Phase 3
- Healthy Volunteers · Phase 1
- Kidney Diseases · Phase 3
- Lung Diseases, Interstitial · Phase 4
- Lupus Erythematosus, Systemic · Phase 4
- Lupus Nephritis · Phase 4
- Maintenance · Phase 4
- Multiple Sclerosis, Relapsing-Remitting · Phase 2
- Myasthenia Gravis · Phase 4
- Neuromyelitis Optica · Phase 3
- Scleroderma, Diffuse · Phase 2
- Scleroderma, Systemic · Phase 4
- Sjogren's Syndrome · Phase 3
- Thrombocytopenia · Phase 2
Mechanism of action
TNFSF13B antagonist
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL5095293 ↗
Also known as
- rc18
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07298928 | N/A | Jan 15, 2026 | Zhejiang University |
| NCT07249632 | Phase 3 | Nov 30, 2025 | Fudan University, Peking University, RemeGen |
| NCT07052981 | Phase 3 | Aug 1, 2025 | Nanjing Medical University |
| NCT07077486 | Phase 4 | Jul 25, 2025 | Huazhong University of Science and Technology, Wuhan Central Hospital, Wuhan University |
| NCT07111338 | Phase 2 | Jul 12, 2025 | Peking University |
| NCT07008196 | Phase 4 | Jun 10, 2025 | Chinese Academy of Medical Sciences, Chinese SLE Treatment And Research Group |
| NCT06827587 | N/A | Feb 28, 2025 | Ningbo Medical Center Lihuili Eastern Hospital, Wenzhou Medical University, Zhejiang University |
| NCT06723548 | Phase 4 | Dec 31, 2024 | Wenzhou Medical University |
| NCT06654596 | N/A | Nov 30, 2024 | Fudan University, Jiao Tong University, Second Military Medical University, Shanghai Longhua Hospital, Sichuan University, Wannan Medical College, Wuhan University, Yijishan Hospital of Wannan Medical College |
| NCT06614985 | Phase 2 | Oct 20, 2024 | Wuhan University |
| NCT06677801 | Phase 4 | Oct 11, 2024 | Zhejiang University |
| NCT06656962 | Phase 1/Phase 2 (Phase 2) | Oct 10, 2024 | Wuhan University |
| NCT06456567 | Phase 3 | Sep 30, 2024 | RemeGen |
| NCT06549959 | Phase 1 | Aug 5, 2024 | RemeGen |
| NCT06510283 | Phase 2 | Aug 1, 2024 | Capital Medical University |
| NCT07098897 | Phase 3 | Aug 1, 2024 | Xuzhou Medical University |
| NCT06456580 | Phase 3 | Jul 17, 2024 | RemeGen |
| NCT06394063 | N/A | Jun 28, 2024 | Jiao Tong University |
| NCT06546540 | Phase 4 | Jun 8, 2024 | Peking University |
| NCT06375005 | Phase 2 | Jun 1, 2024 | Zhejiang University |
Showing 20 of 49 trials
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Organizations
Research & Development (37)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| RemeGen | For profit | 23 | 22 | 4 | 2015 |
| Peking University | Academic/Hospital | 9 | 4 | 3 | 2017 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 8 | 2 | 4 | 2019 |
| Zhejiang University | Academic/Hospital | 6 | 5 | 4 | 2023 |
| Jiao Tong University | Academic/Hospital | 5 | 3 | 2 | 2015 |
| Wuhan University | Academic/Hospital | 4 | 2 | 3 | 2024 |
| Chinese SLE Treatment And Research Group | Academic/Hospital | 3 | 3 | 1 | 2023 |
| Central South University | Academic/Hospital | 2 | 1 | 2 | 2022 |
| Fudan University | Academic/Hospital | 2 | 0 | 2 | 2024 |
| Huazhong University of Science and Technology | Academic/Hospital | 2 | 1 | 2 | 2023 |
| Sichuan University | Academic/Hospital | 2 | 0 | 2 | 2023 |
| Tsinghua University | Academic/Hospital | 2 | 0 | 2 | 2015 |
| Wenzhou Medical University | Academic/Hospital | 2 | 2 | 2 | 2024 |
| Zhengzhou University | Academic/Hospital | 2 | 1 | 1 | 2023 |
| Anhui Medical University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Bengbu Medical College | Academic/Hospital | 1 | 0 | 1 | 2019 |
| Capital Medical University | Academic/Hospital | 1 | 1 | 1 | 2024 |
| Changhai Hospital | Academic/Hospital | 1 | 0 | 1 | 2023 |
| China Academy of Chinese Medical Sciences | Academic/Hospital | 1 | 0 | 1 | 2023 |
| China Medical University | Academic/Hospital | 1 | 0 | 1 | 2023 |
37 organizations
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