racotumomab
Racotumomab is a therapeutic cancer vaccine for the treatment of solid tumors that is currently under clinical development by ReComBio, an international public-private consortium with the participation of the Center of Molecular Immunology at Havana, Cuba (CIM) and researchers from Buenos Aires University and National University of Quilmes in Argentina. It induces the patient's immune system to generate a response against a cancer-specific molecular target with the purpose of blocking tumor growth, slowing disease progression and ultimately increasing patient survival. — Wikipedia
Clinical trial activity
4 trials · 7 clinical orgs · 0 marketing orgs
Earliest trial started Sep 1, 2009 (NCT01240447)
Timeline
Indications
Mechanism of action
- Ganglioside GM3 (NeuGcGM3)INHIBITOR
Ganglioside GM3 (NeuGcGM3) inhibitor
- ganglioside NGNAImmunity, passive
ganglioside NGNA immunity, passive
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaRacotumomab ↗
- ChEMBLCHEMBL1743059 ↗
Also known as
- racotumomab
- racotumomab
- racotumomab
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02998983 | Phase 2 | Nov 1, 2016 | Laboratorio Elea S.A.C.I.F. y A., University of Buenos Aires |
| NCT01598454 | Phase 1 | Feb 1, 2011 | Government of Spain, Laboratorio Elea S.A.C.I.F. y A., University of Buenos Aires |
| NCT01460472 | Phase 3 | Sep 1, 2010 | CIMAB, Cuba, Eurofarma Laboratorios S.A., Innogene Kalbiotech Pte. Ltd, Laboratorio Elea S.A.C.I.F. y A., Recombio SL |
| NCT01240447 | Phase 2 | Sep 1, 2009 | Laboratorio Elea S.A.C.I.F. y A. |
Organizations
Research & Development (7)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Laboratorio Elea S.A.C.I.F. y A. | For profit | 4 | 3 | 3 | 2009 |
| University of Buenos Aires | Academic/Hospital | 2 | 0 | 2 | 2011 |
| CIMAB, Cuba | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Eurofarma Laboratorios S.A. | For profit | 1 | 0 | 1 | 2010 |
| Government of Spain | Government | 1 | 0 | 1 | 2011 |
| Innogene Kalbiotech Pte. Ltd | For profit | 1 | 0 | 1 | 2010 |
| Recombio SL | For profit | 1 | 1 | 1 | 2010 |