pipamperone

Small moleculeexperimental

Pipamperone, sold under the brand name Dipiperon, is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia and as a sleep aid for depression. It is or has been marketed under brand names including Dipiperon, Dipiperal, Piperonil, Piperonyl, and Propitan. Pipamperone was discovered at Janssen Pharmaceutica in 1961, and entered clinical trials in the United States in 1963. — Wikipedia

Clinical trial activity

5 trials · 5 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
4
Phase 3
2
Phase 4
1

Earliest trial started Feb 1, 2008 (NCT00672659)

Timeline

2000s

  1. Jan 1, 2008

    Earliest Phase 2 Sponsor(trial)

2010s

  1. Jan 1, 2011

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

NC(=O)C1(N2CCCCC2)CCN(CCCC(=O)c2ccc(F)cc2)CC1
Mol. weight
375.49 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 1'-(3-(4-fluorobenzoyl)propyl)-(1,4'-bipiperidine) -4'-carboxamide
  • carpiperone
  • carpiperone
  • dipiperal
  • dipiperon
  • dipiperon
  • dipiperone
  • floropipamide
  • floropipamide
  • floropipamide
  • floropipamide
  • fluoropipamide
  • fluoropipamide
  • pipamperone
  • pipamperone
  • pipamperone
  • pipamperone
  • pipamperone
  • pipamperone
  • pipamperone
  • pipamperone
  • pipamperone dihydrochloride
  • pipamperone hcl
  • pipamperone hcl
  • pipamperone hcl
  • pipamperone hydrochloride
  • pipamperon-neuraxpharm
  • pipaneperone
  • pipaneperone
  • r 3345
  • r-3345
  • r-3345

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02435095Phase 4May 1, 2015RWTH Aachen University
NCT02374567Phase 3Jan 1, 2015Gottfried Wilhelm Leibniz Universität Hannover
NCT01450514Phase 2Mar 1, 2012Katholieke Universiteit Leuven, PharmaNeuroBoost N.V.
NCT01312922Phase 3Sep 1, 2011PharmaNeuroBoost N.V.
NCT00672659Phase 2Feb 1, 2008CPS Research, PharmaNeuroBoost N.V.
Showing 5 of 5 trials
Page 1 / 1

Organizations

Research & Development (5)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
PharmaNeuroBoost N.V.For profit3322008
CPS ResearchFor profit1012008
Gottfried Wilhelm Leibniz Universität HannoverAcademic/Hospital1112015
Katholieke Universiteit LeuvenAcademic/Hospital1012012
RWTH Aachen UniversityAcademic/Hospital1112015
5 organizations
Page 1 / 1