pinaverium
Small moleculeexperimental
Pinaverium bromide (INN) is a medication used for functional gastrointestinal disorders. It belongs to a drug group called antispasmodics and acts as a calcium channel blocker in helping to restore the normal contraction process of the bowel. It is most effective when taken for a full course of treatment and is not designed for immediate symptom relief or sporadic, intermittent use. — Wikipedia
Clinical trial activity
5 trials · 5 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
2
Earliest trial started May 1, 2012 (NCT01641224)
Timeline
No events for the selected filters.
Indications
Approved for
Mechanism of action
- Voltage-gated L-type calcium channelINHIBITOR
Voltage-gated L-type calcium channel inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
COc1cc(Br)c(C[N+]2(CCOCCC3CCC4CC3C4(C)C)CCOCC2)cc1OC- Mol. weight
- 511.52 g/mol
- Lipinski Ro5
- 2 violation(s)
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL1909324 ↗
- WikipediaPinaverium bromide ↗
- ChEMBLCHEMBL1909298 ↗
Also known as
- dicetel
- dicetel
- dicetel
- eldicet
- pinaverium
- pinaverium
- pinaverium
- pinaverium
- pinaverium
- pinaverium
- pinaverium
- pinaverium
- pinaverium bromide
- pinaverium bromide
- pinaverium bromide
- pinaverium bromide
- pinaverium bromide
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02833103 | Phase 4 | Jul 1, 2016 | Jiao Tong University |
| NCT02882451 | N/A | Jul 1, 2016 | Changhai Hospital |
| NCT02173964 | Phase 4 | Jul 1, 2014 | Seoul National University |
| NCT02330029 | N/A | Aug 1, 2012 | Jiao Tong University, Macrohard Institute of Health |
| NCT01641224 | N/A | May 1, 2012 | University of Minnesota |
Showing 5 of 5 trials
Page 1 / 1
Organizations
Research & Development (5)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Jiao Tong University | Academic/Hospital | 2 | 1 | 2 | 2012 |
| Changhai Hospital | Academic/Hospital | 1 | 1 | 1 | 2016 |
| Macrohard Institute of Health | Academic/Hospital | 1 | 1 | 1 | 2012 |
| Seoul National University | Academic/Hospital | 1 | 1 | 1 | 2014 |
| University of Minnesota | Academic/Hospital | 1 | 1 | 1 | 2012 |
5 organizations
Page 1 / 1