aglatimagene besadenovec
Gene therapyexperimental
Clinical trial activity
11 trials · 8 clinical orgs · 0 marketing orgs
Phase 1
5
Phase 2
5
Phase 3
3
Phase 4
0
Earliest trial started Sep 1, 2000 (NCT00300521)
Timeline
Indications
Studied for
- Astrocytoma · Phase 2
- Breast Neoplasms · Phase 1
- Carcinoma, Hepatocellular · Phase 3
- Carcinoma, Non-Small-Cell Lung · Phase 2
- Ependymoma · Phase 1
- Glioblastoma · Phase 2
- Glioma · Phase 2
- Liver Transplantation · Phase 2
- Lung Neoplasms · Phase 1
- Mesothelioma · Phase 1
- Ovarian Neoplasms · Phase 1
- Pancreatic Neoplasms · Phase 1
- Pleural Effusion, Malignant · Phase 1
- Prostatic Neoplasms · Phase 3
Mechanism of action
- Oncolytic virusOTHER
Oncolytic virus other
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3544993 ↗
Also known as
- adv-tk
- adv-tk
- aglatimagene besadenovec
- aglatimagene besadenovec
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04495153 | Phase 2 | Oct 13, 2020 | Candel Therapeutics, New York University |
| NCT03131037 | Phase 1 | May 1, 2017 | Candel Therapeutics, University of Pennsylvania |
| NCT02768363 | Phase 2/Phase 3 (Phase 3) | May 1, 2016 | Candel Therapeutics |
| NCT01997190 | Phase 1 | Oct 1, 2013 | Candel Therapeutics, University of Pennsylvania |
| NCT03313596 | Phase 3 | Mar 31, 2013 | Capital Medical University, Huazhong University of Science and Technology |
| NCT01436968 | Phase 3 | Sep 1, 2011 | Candel Therapeutics |
| NCT00634231 | Phase 1 | Apr 1, 2010 | Candel Therapeutics, Harvard University |
| NCT00638612 | Phase 1 | Aug 1, 2008 | Candel Therapeutics, Ohio State University |
| NCT00589875 | Phase 2 | Mar 1, 2007 | Candel Therapeutics, Ohio State University |
| NCT00751270 | Phase 1 | Nov 1, 2005 | Candel Therapeutics, Ohio State University |
| NCT00300521 | Phase 2 | Sep 1, 2000 | Capital Medical University, Huazhong University of Science and Technology, People's Liberation Army of China |
Showing 11 of 11 trials
Page 1 / 1
Organizations
Research & Development (8)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Candel Therapeutics | For profit | 9 | 9 | 3 | 2005 |
| Ohio State University | Academic/Hospital | 3 | 0 | 2 | 2005 |
| Capital Medical University | Academic/Hospital | 2 | 1 | 2 | 2000 |
| Huazhong University of Science and Technology | Academic/Hospital | 2 | 1 | 2 | 2000 |
| University of Pennsylvania | Academic/Hospital | 2 | 0 | 1 | 2013 |
| Harvard University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| New York University | Academic/Hospital | 1 | 0 | 1 | 2020 |
| People's Liberation Army of China | Government | 1 | 0 | 1 | 2000 |
8 organizations
Page 1 / 1