riviciclib
Small moleculeexperimental
Clinical trial activity
11 trials · 37 clinical orgs · 0 marketing orgs
Phase 1
7
Phase 2
7
Phase 3
0
Phase 4
0
Earliest trial started May 1, 2005 (NCT00407498)
Timeline
Indications
Mechanism of action
- Cyclin-dependent kinase 9INHIBITOR
CDK9 inhibitor
- Cyclin-dependent kinase 4INHIBITOR
CDK4 inhibitor
- Cyclin-dependent kinase 1INHIBITOR
CDK1 inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
CN1CCC(c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)C1CO- Mol. weight
- 401.85 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3545283 ↗
Also known as
- p276-00
- p276-00
- p276-00
- riviciclib
- riviciclib
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01903018 | Phase 2 | Jul 1, 2012 | Piramal |
| NCT01333137 | Phase 1 | Aug 1, 2011 | Piramal, University of Southern California |
| NCT00843050 | Phase 2 | Nov 1, 2009 | All India Institute of Medical Sciences, Cancer Care Centers of South Texas , San Antonio, Cancer Care Clinic and Hospital, Nagpur, India, Gabrail Cancer Center, Jaslok Hospital and Research Centre, Mumbai, India, Malabar Institute of Medical Sciences, Mayo Clinic, Meenakshi Ammal Dental College and Hospital, Piramal, Rajiv Gandhi University of Health Sciences, Rutgers University, Tata Memorial Hospital, University of Utah, University of Washington, University of Wisconsin, Vanderbilt University |
| NCT00899054 | Phase 1/Phase 2 (Phase 2) | Aug 1, 2009 | Bhagwan Mahaveer Jain Hospital, Christian Medical College, Vellore, India, Curie Manavata Cancer Center, Nashik, India, GKNM Hospital, Coimbatore, India, Government Medical College, Aurangabad, India, Meenakshi Ammal Dental College and Hospital, Piramal |
| NCT00898287 | Phase 1/Phase 2 (Phase 2) | May 1, 2009 | Central India Cancer Research Institute, Nagpur, Curie Manavata Cancer Center, Nashik, India, Deenanath Mangeshkar Hospital & Research Centre, Global Hospital, Hyderabad, Lifeline Mutispecilaity Hospital, Chennai, India, Meenakshi Ammal Dental College and Hospital, Piramal, Sri Ramachandra Medical College, Chennai |
| NCT00835419 | Phase 2 | May 1, 2009 | Newcastle University, Piramal |
| NCT00547404 | Phase 1 | Dec 1, 2008 | Emory University, Harvard University, New York Medical College, Piramal |
| NCT00824343 | Phase 2 | Sep 1, 2008 | Bhagwan Mahaveer Jain Hospital, Bharat Hospital, Central India Cancer Research Institute, Nagpur, CSM Medical University, Lucknow, Deenanath Mangeshkar Hospital & Research Centre, GKNM Hospital, Coimbatore, India, Jaslok Hospital and Research Centre, Mumbai, India, Piramal, Regional Cancer Centre, Trivandram |
| NCT00882063 | Phase 1/Phase 2 (Phase 2) | Jan 1, 2008 | Piramal |
| NCT00408018 | Phase 1 | Mar 1, 2006 | Global Hospital, Hyderabad, Nizam's Institute of Medical Sciences, Hyderabad, India, Piramal, Tata Memorial Hospital |
| NCT00407498 | Phase 1 | May 1, 2005 | McMaster University, Nizam's Institute of Medical Sciences, Hyderabad, India, Piramal, Queen's University, Belfast |
Showing 11 of 11 trials
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Organizations
Research & Development (37)
37 organizations
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