ornithine oxoglurate
Small moleculeexperimental
Ornithine oxoglutarate (OGO) or ornithine α-ketoglutarate (OKG) is a drug used in liver therapy. It is the salt formed from ornithine and alpha-ketoglutaric acid. It is also used to improve nutritional health in elderly patients. — Wikipedia
Clinical trial activity
1 trials · 3 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Jul 1, 2008 (NCT00645879)
Timeline
2000s
- Jan 1, 2008
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Loading structure…
SMILES
NCCC[C@H](N)C(=O)O.O=C(O)CCC(=O)C(=O)O- Mol. weight
- 278.26 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaOrnithine oxoglutarate ↗
- ChEMBLCHEMBL3138616 ↗
Also known as
- cetornan
- cetornan
- di-l-ornithine-alpha-ketoglutarate
- ornicetil
- ornicetil
- ornithine 2-oxoglurate
- ornithine 2-oxoglutarate
- ornithine alpha ketoglutarate
- ornithine alpha ketoglutarate
- ornithine alpha-ketoglutarate
- ornithine ketoglutarate
- ornithine oxoglurate
- ornithine oxoglurate
- ornithine oxoglurate
- ornithine oxoglurate
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00645879 | Phase 1 | Jul 1, 2008 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), University of Utah |
Showing 1 of 1 trials
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Organizations
Research & Development (3)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Government | 1 | 0 | 1 | 2008 |
| National Institutes of Health (NIH) | Government | 1 | 0 | 1 | 2008 |
| University of Utah | Academic/Hospital | 1 | 1 | 1 | 2008 |
3 organizations
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