aeg35156
Nucleic acidexperimental
Clinical trial activity
9 trials · 11 clinical orgs · 0 marketing orgs
Phase 1
8
Phase 2
6
Phase 3
0
Phase 4
0
Earliest trial started Apr 1, 2005 (NCT00357747)
Timeline
Indications
Studied for
- Breast Neoplasms · Phase 1/Phase 2
- Carcinoma · Phase 1/Phase 2
- Carcinoma, Hepatocellular · Phase 1/Phase 2
- Carcinoma, Non-Small-Cell Lung · Phase 1/Phase 2
- Leukemia · Phase 2
- Leukemia, Lymphocytic, Chronic, B-Cell · Phase 1/Phase 2
- Lymphoma, B-Cell · Phase 1/Phase 2
- Neoplasms · Phase 1
- Pancreas · Phase 1/Phase 2
Mechanism of action
- Inhibitor of apoptosis protein 3ANTISENSE INHIBITOR
XIAP antisense inhibitor
Chemistry & pharmacology
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Also known as
- aeg35156
- aeg35156
- aeg 35156
- gem 640
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01018069 | Phase 2 | Nov 1, 2009 | Aegera Therapeutics, University of Toronto |
| NCT00882869 | Phase 1/Phase 2 (Phase 2) | Mar 1, 2009 | Aegera Therapeutics, Chinese University of Hong Kong, Tuen Mun Hospital, Hong Kong |
| NCT00768339 | Phase 1/Phase 2 (Phase 2) | Sep 1, 2008 | Aegera Therapeutics, The Leukemia and Lymphoma Society, University of Rochester |
| NCT00558545 | Phase 1/Phase 2 (Phase 2) | Nov 1, 2007 | Aegera Therapeutics, Indiana University |
| NCT00558922 | Phase 1/Phase 2 (Phase 2) | Sep 1, 2007 | Aegera Therapeutics, Rocky Mountain Cancer Centers |
| NCT00557596 | Phase 1/Phase 2 (Phase 2) | Sep 1, 2007 | Aegera Therapeutics, TGen Drug Development |
| NCT00385775 | Phase 1 | Jun 1, 2006 | Aegera Therapeutics |
| NCT00372736 | Phase 1 | Jun 1, 2006 | Canadian Cancer Trials Group, McGill University |
| NCT00357747 | Phase 1 | Apr 1, 2005 | Canadian Cancer Trials Group, McGill University |
Showing 9 of 9 trials
Page 1 / 1
Organizations
Research & Development (11)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Aegera Therapeutics | For profit | 7 | 7 | 2 | 2006 |
| Canadian Cancer Trials Group | Academic/Hospital | 2 | 2 | 1 | 2005 |
| McGill University | Academic/Hospital | 2 | 0 | 1 | 2005 |
| Chinese University of Hong Kong | Academic/Hospital | 1 | 0 | 1 | 2009 |
| Indiana University | Academic/Hospital | 1 | 0 | 1 | 2007 |
| Rocky Mountain Cancer Centers | Academic/Hospital | 1 | 0 | 1 | 2007 |
| TGen Drug Development | Academic/Hospital | 1 | 0 | 1 | 2007 |
| The Leukemia and Lymphoma Society | Academic/Hospital | 1 | 0 | 1 | 2008 |
| Tuen Mun Hospital, Hong Kong | Academic/Hospital | 1 | 0 | 1 | 2009 |
| University of Rochester | Academic/Hospital | 1 | 0 | 1 | 2008 |
| University of Toronto | Academic/Hospital | 1 | 0 | 1 | 2009 |
11 organizations
Page 1 / 1