otilonium bromide
Trade name: Spasmomen
Small moleculeexperimental
Otilonium bromide is a drug used to treat abdominal pain caused by irritable bowel syndrome. It is an antispasmodic, which is useful to treat the symptoms of irritable bowel syndrome by reducing abdominal spasms (colic), bloating, pain, and gut motility. — Wikipedia
Clinical trial activity
3 trials · 3 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
3
Earliest trial started Dec 1, 2011 (NCT01629212)
Timeline
No events for the selected filters.
Indications
Approved for
Mechanism of action
- Voltage-gated L-type calcium channelANTAGONIST
Voltage-gated L-type calcium channel antagonist
Chemistry & pharmacology
Loading structure…
SMILES
CCCCCCCCOc1ccccc1C(=O)Nc1ccc(C(=O)OCC[N+](C)(CC)CC)cc1.[Br-]- Mol. weight
- 563.58 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaOtilonium bromide ↗
- ChEMBLCHEMBL2103773 ↗
Also known as
- n-diethylmethylammoniummethyl-p-(2-(n-octyloxy)benzoyl)aminobenzoate bromide
- octylonium
- octylonium bromide
- octylonium bromide
- octylonium bromide
- octylonium bromide
- octylonium iodide
- otilonium bromide
- otilonium bromide
- otilonium bromide
- otilonium bromide
- otilonium bromide
- otilonium bromide
- sp63
- sp63
- spasmomen
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04270487 | Phase 4 | Jul 26, 2018 | Katholieke Universiteit Leuven |
| NCT02576340 | Phase 4 | Jan 1, 2013 | Konya Training and Research Hospital |
| NCT01629212 | Phase 4 | Dec 1, 2011 | Daewoong Pharmaceutical Co. LTD. |
Showing 3 of 3 trials
Page 1 / 1
Organizations
Research & Development (3)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Daewoong Pharmaceutical Co. LTD. | For profit | 1 | 1 | 1 | 2011 |
| Katholieke Universiteit Leuven | Academic/Hospital | 1 | 1 | 1 | 2018 |
| Konya Training and Research Hospital | Academic/Hospital | 1 | 1 | 1 | 2013 |
3 organizations
Page 1 / 1