dodecafluoropentane

Small moleculeexperimental

Perfluoropentane (PFP) or dodecafluoropentane; also known as Perflenapent (INN/USAN) is a fluorocarbon, the fluorinated analogue of pentane. It is a liquid that boils at slightly over room temperature. — Wikipedia

Clinical trial activity

5 trials · 7 clinical orgs · 0 marketing orgs

Phase 1
3
Phase 2
1
Phase 3
1
Phase 4
0

Earliest trial started May 1, 2014 (NCT02189109)

Timeline

2010s

  1. Jan 1, 2014

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2019

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

  • Unspecified targetOTHER

    Ultrasound contrast agent

  • Unspecified targetUnclear

    Unclear

Chemistry & pharmacology

Loading structure…

SMILES

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
Mol. weight
288.03 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 2h,3h-perfluoropentane
  • dodecafluoropentane
  • dodecafluoropentane
  • dodecafluoropentane
  • dodecafluoropentane
  • dodecafluoropentane
  • nvx-108
  • nvx-108
  • nvx-108
  • perflenapent
  • perflenapent
  • perflenapent
  • perflenapent
  • perflenapent
  • perfluoropentane
  • perfluoropentane

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06658535Phase 1Oct 31, 2024NuvOx Pharma Pty Ltd
NCT05389748Phase 2/Phase 3 (Phase 3)Apr 1, 2023NuvOx Pharma Pty Ltd, Stanford University, University of Arkansas, University of Washington
NCT03862430Phase 2Mar 31, 2019NuvOx Pharma Pty Ltd
NCT02963376Phase 1Dec 1, 2016Hoosier Cancer Research Network
NCT02189109Phase 1May 1, 2014Nucleus Network Ltd, NuvOx Pharma Pty Ltd, The Alfred Hospital
Showing 5 of 5 trials
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Organizations

Research & Development (7)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
NuvOx Pharma Pty LtdFor profit4432014
Hoosier Cancer Research NetworkAcademic/Hospital1112016
Nucleus Network LtdFor profit1012014
Stanford UniversityAcademic/Hospital1012023
The Alfred HospitalAcademic/Hospital1012014
University of ArkansasAcademic/Hospital1012023
University of WashingtonAcademic/Hospital1012023
7 organizations
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