necator americanus
Necator americanus is a species of hookworm commonly known as the New World hookworm. Like other hookworms, it is a member of the phylum Nematoda. It is an obligatory parasitic nematode that lives in the small intestine of human hosts. Necatoriasis—a type of helminthiasis—is the term for the condition of being host to an infestation of a species of Necator. Since N. americanus and Ancylostoma duodenale are the two species of hookworms that most commonly infest humans, they are usually dealt with under the collective heading of "hookworm infection". They differ most obviously in geographical distribution, structure of mouthparts, and relative size. — Wikipedia
Clinical trial activity
7 trials · 12 clinical orgs · 0 marketing orgs
Earliest trial started Oct 1, 2007 (NCT00671138)
Timeline
Indications
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaNecator americanus ↗
Also known as
- necator americanus
- necator americanus hookworm larvae
- necator americanus l3 larvae
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06478498 | N/A | Oct 1, 2024 | Leiden University |
| NCT03257072 | N/A | Jan 10, 2018 | Leiden University |
| NCT03172975 | Phase 2 | Jul 15, 2017 | Baylor University, George Washington University, National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT03126552 | N/A | Apr 1, 2017 | Leiden University |
| NCT01940757 | Phase 1 | Jan 1, 2015 | Baylor University, George Washington University |
| NCT01661933 | Phase 1/Phase 2 (Phase 2) | Aug 1, 2012 | James Cook University Hospital, Middlesbrough, UK, Logan University, National Health and Medical Research Council, Australia, University of Queensland |
| NCT00671138 | Phase 2 | Oct 1, 2007 | Envoi Pathology, James Cook University Hospital, Middlesbrough, UK, The Broad Foundation, University of Queensland, University of Sydney, Walter and Eliza Hall Institute of Medical Research |
Organizations
Research & Development (12)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Leiden University | Academic/Hospital | 3 | 3 | 1 | 2017 |
| Baylor University | Academic/Hospital | 2 | 2 | 2 | 2015 |
| George Washington University | Academic/Hospital | 2 | 0 | 2 | 2015 |
| James Cook University Hospital, Middlesbrough, UK | Academic/Hospital | 2 | 0 | 1 | 2007 |
| University of Queensland | Academic/Hospital | 2 | 1 | 1 | 2007 |
| Envoi Pathology | Academic/Hospital | 1 | 0 | 1 | 2007 |
| Logan University | Academic/Hospital | 1 | 0 | 1 | 2012 |
| National Health and Medical Research Council, Australia | Government | 1 | 0 | 1 | 2012 |
| National Institute of Allergy and Infectious Diseases (NIAID) | Government | 1 | 0 | 1 | 2017 |
| The Broad Foundation | Academic/Hospital | 1 | 0 | 1 | 2007 |
| University of Sydney | Academic/Hospital | 1 | 1 | 1 | 2007 |
| Walter and Eliza Hall Institute of Medical Research | Academic/Hospital | 1 | 0 | 1 | 2007 |