mk-0686

Small moleculeexperimental

Clinical trial activity

3 trials · 1 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
3
Phase 3
0
Phase 4
0

Earliest trial started Jul 1, 2004 (NCT00533403)

Timeline

2000s

  1. Jan 1, 2004

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

COC(=O)c1c(Cl)cccc1-c1ccc([C@@H](C)NC(=O)C2(NC(=O)C(F)(F)F)CC2)c(F)c1
Mol. weight
486.85 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • methyl 3-chloro-3'-fluoro-4'-(1-(((1-((trifluoroacetyl)amino)cyclopropyl)carbonyl)amino)ethyl)-1,1'-biphenyl-2-carboxylate
  • methyl cftbc
  • mk0686
  • mk0686
  • mk0686
  • mk0686
  • mk 0686
  • mk-0686
  • mk-0686
  • mk-0686
  • mk-0686

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT00282763Phase 2Dec 1, 2005Merck
NCT00296569Phase 2Sep 1, 2005Merck
NCT00533403Phase 2Jul 1, 2004Merck
Showing 3 of 3 trials
Page 1 / 1

Organizations

Research & Development (1)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
MerckFor profit3312004
1 organizations
Page 1 / 1