mitoguazone
Small moleculeexperimental
Mitoguazone is a drug used in chemotherapy. — Wikipedia
Clinical trial activity
2 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
2
Phase 3
1
Phase 4
0
Earliest trial started Nov 2, 1999 (NCT00002348)
Timeline
Indications
Mechanism of action
- S-adenosylmethionine decarboxylase 1INHIBITOR
AMD1 inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
CC(/C=N/NC(=N)N)=N\NC(=N)N- Mol. weight
- 184.21 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaMitoguazone ↗
- ChEMBLCHEMBL216913 ↗
Also known as
- methylglyoxal bis(amidinohydrazone)
- methylglyoxal bis(guanylhydrazone)
- mitoguazone
- mitoguazone
- mitoguazone
- mitoguazone
- mitoguazone
- mitoguazone
- mitoguazone
- mitoguazone
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00920153 | Phase 3 | May 1, 2008 | French Innovative Leukemia Organisation |
| NCT00002348 | Phase 2 | Nov 2, 1999 | Genzyme |
Showing 2 of 2 trials
Page 1 / 1
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| French Innovative Leukemia Organisation | Academic/Hospital | 1 | 1 | 1 | 2008 |
| Genzyme | For profit | 1 | 1 | 1 | 1999 |
2 organizations
Page 1 / 1