metacavir
Small moleculeexperimental
Clinical trial activity
3 trials · 5 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Dec 1, 2010 (NCT03173599)
Timeline
Indications
Studied for
Mechanism of action
- Reverse transcriptaseINHIBITOR
Reverse transcriptase inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
COc1nc(N)nc2c1ncn2[C@H]1CC[C@@H](CO)O1- Mol. weight
- 265.27 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL243716 ↗
Also known as
- 2-amino-9-(2,3-dideoxy-2,3-dihydroarabinofuranosyl)-6-methoxy-9h-purine
- metacavir
- metacavir
- metacavir
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02965859 | Phase 2 | Dec 1, 2012 | Guangzhou Yipinhong Pharmaceutical CO.,LTD, Nanjing Medical University, People's Liberation Army of China, Wannan Medical College |
| NCT03180333 | Phase 1 | Mar 1, 2012 | Guangzhou Yipinhong Pharmaceutical CO.,LTD, Nanjing Medical University |
| NCT03173599 | Phase 1 | Dec 1, 2010 | Guangzhou Yipinhong Pharmaceutical CO.,LTD, Jiao Tong University |
Showing 3 of 3 trials
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Organizations
Research & Development (5)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Guangzhou Yipinhong Pharmaceutical CO.,LTD | For profit | 3 | 3 | 2 | 2010 |
| Nanjing Medical University | Academic/Hospital | 2 | 0 | 2 | 2012 |
| Jiao Tong University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| People's Liberation Army of China | Government | 1 | 0 | 1 | 2012 |
| Wannan Medical College | Academic/Hospital | 1 | 0 | 1 | 2012 |
5 organizations
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