melanocytes
Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer of the skin's epidermis, the middle layer of the eye, the inner ear, vaginal epithelium, meninges, bones, and heart found in many mammals and birds. Melanin is a dark pigment primarily responsible for skin color. Once synthesized, melanin is contained in special organelles called melanosomes which can be transported to nearby keratinocytes to induce pigmentation. Thus darker skin tones have more melanosomes present than lighter skin tones. Functionally, melanin serves as protection against UV radiation. Melanocytes also have a role in the immune system. — Wikipedia
Clinical trial activity
2 trials · 4 clinical orgs · 0 marketing orgs
Earliest trial started Feb 1, 2009 (NCT00631865)
Timeline
Indications
Studied for
Mechanism of action
- MelanocyteTissue restoration
tissue restoration - melanocyte
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaMelanocyte ↗
Also known as
- melanocyte
- melanocyte
- melanocytes
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01923142 | Phase 2 | Jan 1, 2014 | ARIV Onlus, Centro Studi Gised |
| NCT00631865 | Phase 3 | Feb 1, 2009 | Firoozgar Hospital, Royan Institute |
Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| ARIV Onlus | Academic/Hospital | 1 | 0 | 1 | 2014 |
| Centro Studi Gised | Academic/Hospital | 1 | 1 | 1 | 2014 |
| Firoozgar Hospital | Academic/Hospital | 1 | 0 | 1 | 2009 |
| Royan Institute | Academic/Hospital | 1 | 1 | 1 | 2009 |