melanocytes

Cell therapyexperimental

Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer of the skin's epidermis, the middle layer of the eye, the inner ear, vaginal epithelium, meninges, bones, and heart found in many mammals and birds. Melanin is a dark pigment primarily responsible for skin color. Once synthesized, melanin is contained in special organelles called melanosomes which can be transported to nearby keratinocytes to induce pigmentation. Thus darker skin tones have more melanosomes present than lighter skin tones. Functionally, melanin serves as protection against UV radiation. Melanocytes also have a role in the immune system. — Wikipedia

Clinical trial activity

2 trials · 4 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
2
Phase 3
1
Phase 4
0

Earliest trial started Feb 1, 2009 (NCT00631865)

Timeline

2000s

  1. Jan 1, 2009

    Earliest Phase 3 Sponsor(trial)

2010s

  1. Jan 1, 2014

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

  • MelanocyteTissue restoration

    tissue restoration - melanocyte

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • melanocyte
  • melanocyte
  • melanocytes

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT01923142Phase 2Jan 1, 2014ARIV Onlus, Centro Studi Gised
NCT00631865Phase 3Feb 1, 2009Firoozgar Hospital, Royan Institute
Showing 2 of 2 trials
Page 1 / 1

Organizations

Research & Development (4)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
ARIV OnlusAcademic/Hospital1012014
Centro Studi GisedAcademic/Hospital1112014
Firoozgar HospitalAcademic/Hospital1012009
Royan InstituteAcademic/Hospital1112009
4 organizations
Page 1 / 1