lucerastat

Small moleculeexperimental

Clinical trial activity

7 trials · 2 clinical orgs · 0 marketing orgs

Phase 1
5
Phase 2
2
Phase 3
2
Phase 4
0

Earliest trial started Oct 1, 2002 (NCT02944487)

Timeline

2000s

  1. Jan 1, 2002

    Earliest Phase 1 Sponsor(trial)

2010s

  1. Jan 1, 2018

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CCCCN1C[C@H](O)[C@@H](O)[C@@H](O)[C@H]1CO
Mol. weight
219.28 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • lucerastat
  • lucerastat

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT03832452Phase 1Feb 14, 2019Idorsia Pharmaceuticals Ltd.
NCT03737214Phase 3Dec 18, 2018Idorsia Pharmaceuticals Ltd.
NCT03425539Phase 3Jun 21, 2018Idorsia Pharmaceuticals Ltd.
NCT03380455Phase 1Jan 9, 2018Idorsia Pharmaceuticals Ltd.
NCT02930655Phase 1Feb 1, 2015Actelion
NCT02944474Phase 1Dec 1, 2003Actelion
NCT02944487Phase 1Oct 1, 2002Actelion
Showing 7 of 7 trials
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Organizations

Research & Development (2)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Idorsia Pharmaceuticals Ltd.For profit4422018
ActelionFor profit3312002
2 organizations
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