altu-135
Recombinant proteinexperimental
Clinical trial activity
8 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
7
Phase 3
6
Phase 4
1
Earliest trial started Jun 1, 2004 (NCT00095732)
Timeline
Indications
Approved for
Mechanism of action
- Regenerating islet-derived protein 3-alphaSupplementation
REG3A supplementation
- Alpha-amylase 2BSupplementation
Alpha-amylase 2B (AMY2B) supplementation
- TriglycerideHYDROLYTIC ENZYME
Triglyceride hydrolytic enzyme
Lipases catalyse the hydrolysis of lipids.
- StarchHYDROLYTIC ENZYME
Starch hydrolytic enzyme
Amylases catalyse the hydrolysis of polyssacharides into sugars.
- PolypeptidesPROTEOLYTIC ENZYME
Polypeptides proteolytic enzyme
Proteases catalyse the hydrolysis of proteins into smaller polypeptides or amino acids.
- Lysosomal acid lipase/cholesteryl ester hydrolaseSupplementation
LIPA supplementation
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- NCATS6435YY37C0 ↗
- ChEMBLCHEMBL2108703 ↗
- NCATS9VP88M3N3O ↗
Also known as
- altu-135
- altu-135
- altu-135
- liprotamase
- liprotamase
- liprotamase lipase
- theraclec
- trizytek
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03051490 | Phase 3 | Apr 28, 2017 | Anthera Pharmaceuticals |
| NCT02823964 | Phase 4 | Sep 1, 2016 | Anthera Pharmaceuticals |
| NCT02734810 | Phase 3 | Jun 1, 2016 | Anthera Pharmaceuticals |
| NCT02279498 | Phase 3 | Jun 1, 2015 | Anthera Pharmaceuticals |
| NCT00500084 | Phase 3 | Dec 1, 2007 | Anthera Pharmaceuticals |
| NCT00449904 | Phase 3 | Jun 1, 2007 | Anthera Pharmaceuticals |
| NCT00449878 | Phase 3 | May 1, 2007 | Anthera Pharmaceuticals |
| NCT00095732 | Phase 2 | Jun 1, 2004 | Anthera Pharmaceuticals, Cystic Fibrosis Foundation Therapeutics |
Showing 8 of 8 trials
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Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Anthera Pharmaceuticals | For profit | 8 | 8 | 3 | 2004 |
| Cystic Fibrosis Foundation Therapeutics | Academic/Hospital | 1 | 0 | 1 | 2004 |
2 organizations
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