aceneuramic acid

Small moleculeexperimental

N-Acetylneuraminic acid is the predominant sialic acid found in human cells, and many mammalian cells. Other forms, such as N-Glycolylneuraminic acid, may also occur in cells. — Wikipedia

Clinical trial activity

4 trials · 3 clinical orgs · 0 marketing orgs

Phase 1
1
Phase 2
3
Phase 3
2
Phase 4
0

Earliest trial started Nov 1, 2010 (NCT01236898)

Timeline

2010s

  1. Jan 1, 2010

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2016

    Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2016

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CC(=O)N[C@@H]([C@@H](O)[C@H](O)[C@H](O)CO)[C@@H](O)CC(=O)C(=O)O
Mol. weight
309.27 g/mol
Lipinski Ro5
1 violation(s)
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • aceneuramic acid
  • aceneuramic acid
  • aceneuramic acid
  • ux-001

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04671472Phase 3Feb 8, 2021Nobel Pharmaceuticals
NCT02731690Phase 2Jun 1, 2016Ultragenyx Inc.
NCT02736188Phase 3Apr 1, 2016Ultragenyx Inc.
NCT01236898Phase 1Nov 1, 2010Tohoku University
Showing 4 of 4 trials
Page 1 / 1

Organizations

Research & Development (3)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Ultragenyx Inc.For profit2222016
Nobel PharmaceuticalsFor profit1112021
Tohoku UniversityAcademic/Hospital1112010
3 organizations
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