kava
Botanicalexperimental
Kavalactones are a class of lactone compounds found in kava roots and Alpinia zerumbet and in several Gymnopilus, Phellinus and Inonotus fungi. Some kavalactones are bioactive. They are responsible for the psychoactive, analgesic, euphoric and sedative effects of kava. — Wikipedia
Clinical trial activity
12 trials · 13 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
5
Phase 3
0
Phase 4
2
Earliest trial started Jan 1, 2001 (NCT00009542)
Timeline
Indications
Approved for
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaKavalactone ↗
- WikipediaKava ↗
Also known as
- kava
- kava
- kava
- kava
- kavalactones
- methysticum
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07219186 | Early Phase 1 (Phase 1) | Jan 31, 2026 | National Institute on Aging (NIA), University of Florida |
| NCT06213298 | Early Phase 1 (Phase 1) | Feb 1, 2025 | University of Minnesota |
| NCT05814055 | Phase 2 | Feb 29, 2024 | National Center for Complementary and Integrative Health (NCCIH), University of Florida |
| NCT06177535 | N/A | Jan 31, 2024 | Mayo Clinic |
| NCT05381025 | N/A | May 11, 2022 | Advanced Pattern Analysis & Countermeasures Group, Thorne HealthTech, Inc |
| NCT05081882 | Phase 2 | Dec 31, 2021 | Florida Department of Health, University of Florida |
| NCT03606655 | Phase 2 | Oct 31, 2018 | University of Florida |
| NCT02500472 | N/A | Dec 3, 2015 | University of Minnesota |
| NCT02219880 | Phase 4 | Oct 13, 2015 | Swinburne University, University of Melbourne, University of Queensland |
| NCT00451516 | Phase 2 | Mar 1, 2007 | University of Queensland |
| NCT00083980 | Phase 2 | Jun 1, 2002 | Duke University, National Center for Complementary and Integrative Health (NCCIH) |
| NCT00009542 | Phase 4 | Jan 1, 2001 | National Institutes of Health (NIH) |
Showing 12 of 12 trials
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Organizations
Research & Development (13)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Florida | Academic/Hospital | 4 | 4 | 2 | 2018 |
| National Center for Complementary and Integrative Health (NCCIH) | Government | 2 | 1 | 1 | 2002 |
| University of Minnesota | Academic/Hospital | 2 | 2 | 2 | 2015 |
| University of Queensland | Academic/Hospital | 2 | 1 | 2 | 2007 |
| Advanced Pattern Analysis & Countermeasures Group | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Duke University | Academic/Hospital | 1 | 0 | 1 | 2002 |
| Florida Department of Health | Government | 1 | 0 | 1 | 2021 |
| Mayo Clinic | Academic/Hospital | 1 | 1 | 1 | 2024 |
| National Institute on Aging (NIA) | Government | 1 | 0 | 1 | 2026 |
| National Institutes of Health (NIH) | Government | 1 | 1 | 1 | 2001 |
| Swinburne University | Academic/Hospital | 1 | 0 | 1 | 2015 |
| Thorne HealthTech, Inc | For profit | 1 | 1 | 1 | 2022 |
| University of Melbourne | Academic/Hospital | 1 | 1 | 1 | 2015 |
13 organizations
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