iobitridol
Trade name: Xenetix
Small moleculeexperimentalImaging agent
Iobitridol is a pharmaceutical drug used as an iodine-based radiocontrast agent in X-ray imaging. It is injected into blood vessels, joints, or body cavities such as the uterus, and filtered out by the kidneys. Its most common adverse effect is nausea. Severe allergic reactions are rare. — Wikipedia
Clinical trial activity
7 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
0
Phase 3
0
Phase 4
5
Earliest trial started May 1, 2006 (NCT00347022)
Timeline
2010s
- Jan 1, 2013
Earliest Phase 1 Sponsor(trial)
Indications
Approved for
Mechanism of action
- Unspecified targetContrast agent
contrast agent
Chemistry & pharmacology
Loading structure…
SMILES
CN(CC(O)CO)C(=O)c1c(I)c(NC(=O)C(CO)CO)c(I)c(C(=O)N(C)CC(O)CO)c1I- Mol. weight
- 835.17 g/mol
- Lipinski Ro5
- 2 violation(s)
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaIobitridol ↗
- ChEMBLCHEMBL2107212 ↗
Also known as
- 5-(3-hydroxy-2-hydroxymethylpropionamido)-n,n'-dimethyl-n,n'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide
- iobitridol
- iobitridol
- iobitridol
- iobitridol
- iobitridol
- iobitridol
- iobitridol
- iobitridol
- xenetix
- xenetix
- xenetix
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04027556 | N/A | Jun 27, 2019 | Seoul National University, Siemens |
| NCT01908309 | Early Phase 1 (Phase 1) | Apr 1, 2013 | Azienda Sanitaria Locale 9, Grosseto |
| NCT01639703 | Phase 4 | Apr 30, 2012 | Guerbet |
| NCT01255722 | Phase 4 | Nov 1, 2010 | Guerbet, Kantonsspital Lucerne |
| NCT01254552 | Phase 4 | Aug 1, 2010 | Guerbet, University of Ulsan |
| NCT00382317 | Phase 4 | Aug 1, 2006 | Guerbet |
| NCT00347022 | Phase 4 | May 1, 2006 | Guerbet |
Showing 7 of 7 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Guerbet | For profit | 5 | 5 | 1 | 2006 |
| Azienda Sanitaria Locale 9, Grosseto | Government | 1 | 1 | 1 | 2013 |
| Kantonsspital Lucerne | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Seoul National University | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Siemens | For profit | 1 | 0 | 1 | 2019 |
| University of Ulsan | Academic/Hospital | 1 | 0 | 1 | 2010 |
6 organizations
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