idarucizumab

Trade name: praxbind

mAbapprovedOrphan Drug FDABreakthrough Therapy FDA

Approved

Oct 16, 2015

Idarucizumab, sold under the brand name Praxbind, is a monoclonal antibody used as a reversal agent for dabigatran. — Wikipedia

Clinical trial activity

8 trials · 1 clinical orgs · 1 marketing orgs

Phase 1
4
Phase 2
4
Phase 3
4
Phase 4
0

Earliest trial started Sep 1, 2012 (NCT01688830)

Timeline

2010s

  1. Jan 1, 2012

    Boehringer Ingelheim — Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2014

    Boehringer Ingelheim — Earliest Phase 3 Sponsor(trial)

  3. May 28, 2015

    Orphan Drug Designation

  4. Oct 16, 2015

    Boehringer Ingelheim — Earliest FDA Approval

  5. Oct 16, 2015

    Boehringer Ingelheim — Marketing Organization

  6. Oct 16, 2015

    Boehringer Ingelheim — NDA Organization

Indications

Approved for

Mechanism of action

Approval history

  • approvedAcceleratedBreakthroughOct 16, 2015

Chemistry & pharmacology

Chirality
Single Stereoisomer
Inorganic
No
Polymer
No
Delivery
Parenteral
Availability
Prescription Only
Multi-specific
No

Oral

No

Parenteral

Yes

Topical

No

First in class

Sources

Also known as

  • adabi-fab
  • bi 655075
  • bi-655075
  • bi-655075
  • idarucizumab
  • idarucizumab
  • idarucizumab
  • idarucizumab
  • idarucizumab
  • idarucizumab
  • idarucizumab
  • idarucizumab
  • idarucizumab
  • idarucizumab
  • praxbind
  • praxbind
  • praxbind
  • praxbind

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT03343704Phase 3Mar 26, 2018Boehringer Ingelheim
NCT03086356Phase 1May 10, 2017Boehringer Ingelheim
NCT02815670Phase 3Sep 7, 2016Boehringer Ingelheim
NCT02831660Phase 3Jul 1, 2016Boehringer Ingelheim
NCT02104947Phase 3May 1, 2014Boehringer Ingelheim
NCT02028780Phase 1Jan 1, 2014Boehringer Ingelheim
NCT01955720Phase 1Sep 1, 2013Boehringer Ingelheim
NCT01688830Phase 1Sep 1, 2012Boehringer Ingelheim
Showing 8 of 8 trials
Page 1 / 1

Organizations

Research & Development (1)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Boehringer IngelheimFor profit8822012
1 organizations
Page 1 / 1

Marketing (2)

OrganizationOrg typeRelationshipDate
Boehringer IngelheimFor profitMKTGOct 16, 2015
Boehringer IngelheimFor profitNDAOct 16, 2015