hydroxytyrosol
Botanicalexperimental
Hydroxytyrosol is an organic compound with the formula (HO)2C6H3CH2CH2OH. It is a phenylethanoid, i.e. a relative of phenethyl alcohol. Its derivatives are found in a variety of natural sources, notably olive oils and wines. Hydroxytyrosol is a colorless solid, although samples often turn beige during storage. It is a derivative, formally speaking, of catechol. — Wikipedia
Clinical trial activity
18 trials · 20 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
1
Phase 3
1
Phase 4
1
Earliest trial started Oct 1, 2010 (NCT01381354)
Timeline
Indications
Approved for
Mechanism of action
- Unspecified targetAntioxidant
antioxidant
Chemistry & pharmacology
Loading structure…
SMILES
OCCc1ccc(O)c(O)c1- Mol. weight
- 154.16 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaHydroxytyrosol ↗
- ChEMBLCHEMBL485747 ↗
- ChEMBLCHEMBL1950045 ↗
Also known as
- 2-(3,4-dihydroxyphenyl)ethanol
- 3,4-dihydroxyphenylethanol
- beta-3,4-dihydroxyphenylethyl alcohol
- dopet
- hydroxytyrosol
- hydroxytyrosol
- hydroxytyrosol
- hydroxytyrosol
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07074548 | N/A | Jul 10, 2025 | University of Indonesia |
| NCT07298759 | N/A | Jun 11, 2025 | University of Indonesia |
| NCT06992323 | N/A | Feb 17, 2025 | Government of Spain, Olivenova Health Sl |
| NCT06833866 | Phase 1 | Dec 4, 2024 | Methodist Cancer Center, Houston, Texas, The University of Texas, Dallas |
| NCT06735222 | N/A | Nov 18, 2024 | Government of Spain, Olivenova Health Sl |
| NCT06295913 | N/A | Dec 1, 2023 | Government of Spain |
| NCT05472753 | N/A | Nov 16, 2022 | Government of Spain, University of Malaga |
| NCT06319417 | N/A | Apr 15, 2022 | Universidad Católica San Antonio de Murcia |
| NCT05679310 | N/A | Feb 10, 2022 | University of Ioannina |
| NCT04876261 | N/A | May 10, 2021 | Antonio e Bandino Lo Franco Soc. Agr. Sempl., Daacro, Institut Kurz GmbH |
| NCT04520126 | N/A | Dec 1, 2020 | University of Athens |
| NCT04317079 | N/A | Oct 30, 2017 | University of Athens |
| NCT02842567 | Phase 3 | Sep 1, 2016 | Bambino Gesù Hospital and Research Institute |
| NCT02273622 | N/A | Oct 1, 2014 | Government of Spain |
| NCT02068092 | N/A | Dec 1, 2013 | Methodist Cancer Center, Houston, Texas, The Methodist Hospital System |
| NCT01983943 | N/A | Aug 1, 2013 | Mayo Clinic |
| NCT02042742 | Phase 4 | Apr 1, 2013 | Universidad Autonoma de Madrid |
| NCT01381354 | Phase 1 | Oct 1, 2010 | DJO Incorporated, Pinnaclife Inc., TZ Press, LLC, University of Iowa |
Showing 18 of 18 trials
Page 1 / 1
Organizations
Research & Development (20)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Government of Spain | Government | 5 | 5 | 1 | 2014 |
| Methodist Cancer Center, Houston, Texas | Academic/Hospital | 2 | 0 | 2 | 2013 |
| Olivenova Health Sl | Academic/Hospital | 2 | 0 | 1 | 2024 |
| University of Athens | Academic/Hospital | 2 | 2 | 1 | 2017 |
| University of Indonesia | Academic/Hospital | 2 | 2 | 1 | 2025 |
| Antonio e Bandino Lo Franco Soc. Agr. Sempl. | Academic/Hospital | 1 | 0 | 1 | 2021 |
| Bambino Gesù Hospital and Research Institute | Academic/Hospital | 1 | 1 | 1 | 2016 |
| Daacro | For profit | 1 | 1 | 1 | 2021 |
| DJO Incorporated | For profit | 1 | 0 | 1 | 2010 |
| Institut Kurz GmbH | Academic/Hospital | 1 | 0 | 1 | 2021 |
| Mayo Clinic | Academic/Hospital | 1 | 1 | 1 | 2013 |
| Pinnaclife Inc. | For profit | 1 | 0 | 1 | 2010 |
| The Methodist Hospital System | Academic/Hospital | 1 | 1 | 1 | 2013 |
| The University of Texas, Dallas | Academic/Hospital | 1 | 1 | 1 | 2024 |
| TZ Press, LLC | For profit | 1 | 0 | 1 | 2010 |
| Universidad Autonoma de Madrid | Academic/Hospital | 1 | 1 | 1 | 2013 |
| Universidad Católica San Antonio de Murcia | Academic/Hospital | 1 | 1 | 1 | 2022 |
| University of Ioannina | Academic/Hospital | 1 | 1 | 1 | 2022 |
| University of Iowa | Academic/Hospital | 1 | 1 | 1 | 2010 |
| University of Malaga | Academic/Hospital | 1 | 0 | 1 | 2022 |
20 organizations
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