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leptin

Small moleculeexperimental

Leptin, also known as obese protein, is a protein hormone predominantly made by adipocytes. Its primary role is likely to regulate long-term energy balance. — Wikipedia

Clinical trial activity

18 trials · 23 clinical orgs · 0 marketing orgs

Phase 1
4
Phase 2
8
Phase 3
2
Phase 4
1

Earliest trial started Aug 1, 1998 (NCT01207934)

Timeline

2000s

  1. Jan 1, 2000

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2000

    Earliest Phase 3 Sponsor(trial)

  3. Jan 1, 2002

    Earliest Phase 1 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • leptin
  • leptin
  • leptin
  • leptin a

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04443790Phase 2Apr 10, 2015Government College University Faisalabad, Hamdard University, Shifa Ul Mulk Memorial Hospital
NCT01268644Phase 1Sep 1, 2010Amylin, Juvenile Diabetes Research Foundation, The University of Texas, Dallas
NCT01155180Phase 2Jul 1, 2008Harvard University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00710814Phase 1/Phase 2 (Phase 2)Apr 1, 2008Amylin, Columbia University, National Center for Research Resources (NCRR), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00362440Phase 2Aug 1, 2006American Diabetes Association, Harvard University
NCT00896298Phase 2/Phase 3 (Phase 3)Apr 1, 2006The University of Texas, Dallas
NCT00691158N/AJan 1, 2006Oregon Health and Science University
NCT04374500Early Phase 1 (Phase 1)Jan 1, 2006Umea University, University of Edinburgh
NCT00121433Phase 4Sep 1, 2004Amgen, University of Michigan
NCT01257841N/ANov 1, 2002Harvard University, Massachusetts Institute of Technology
NCT00265980N/AJul 1, 2002Columbia University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT01275053Phase 1Jul 1, 2002Harvard University
NCT00027456Phase 2Nov 1, 2001National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00050791Phase 2Mar 1, 2001Columbia University, Cornell University, Rockefeller University, St. Luke's-Roosevelt Hospital Center
NCT01710722N/AFeb 1, 2001Amgen, University of Vermont
NCT00073242Phase 3Jul 1, 2000National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00005905Phase 2Jun 1, 2000National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT01207934N/AAug 1, 1998Amgen, National Institutes of Health (NIH), Washington University in St. Louis
Showing 18 of 18 trials
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Organizations

Research & Development (23)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Government6332000
Harvard UniversityAcademic/Hospital4432002
AmgenFor profit3021998
Columbia UniversityAcademic/Hospital3222001
AmylinFor profit2022008
The University of Texas, DallasAcademic/Hospital2222006
American Diabetes AssociationAcademic/Hospital1012006
Cornell UniversityAcademic/Hospital1012001
Government College University FaisalabadAcademic/Hospital1012015
Hamdard UniversityAcademic/Hospital1012015
Juvenile Diabetes Research FoundationAcademic/Hospital1012010
Massachusetts Institute of TechnologyAcademic/Hospital1012002
National Center for Research Resources (NCRR)Government1012008
National Institutes of Health (NIH)Government1011998
Oregon Health and Science UniversityAcademic/Hospital1112006
Rockefeller UniversityAcademic/Hospital1112001
Shifa Ul Mulk Memorial HospitalAcademic/Hospital1112015
St. Luke's-Roosevelt Hospital CenterAcademic/Hospital1012001
Umea UniversityAcademic/Hospital1112006
University of EdinburghAcademic/Hospital1012006
23 organizations
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