gonyautoxin
Botanicalexperimental
Gonyautoxins (GTX) are a few similar toxic molecules that are naturally produced by algae. They are part of the group of saxitoxins, a large group of neurotoxins along with a molecule that is also referred to as saxitoxin (STX), neosaxitoxin (NSTX) and decarbamoylsaxitoxin (dcSTX). Currently eight molecules are assigned to the group of gonyautoxins, known as gonyautoxin 1 (GTX-1) to gonyautoxin 8 (GTX-8). Ingestion of gonyautoxins through consumption of mollusks contaminated by toxic algae can cause a human illness called paralytic shellfish poisoning (PSP). — Wikipedia
Clinical trial activity
4 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
3
Phase 3
1
Phase 4
0
Earliest trial started Sep 1, 2004 (NCT00276952)
Timeline
Indications
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaGonyautoxin ↗
Also known as
- gonyautoxin
- gonyautoxin
- gonyautoxin
- gonyautoxins
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04799041 | Phase 1/Phase 2 (Phase 2) | Oct 11, 2019 | Algenis SpA, Hospital San José |
| NCT03025594 | Phase 3 | Jan 1, 2017 | University of Chile |
| NCT03655522 | Phase 1 | May 14, 2015 | Algenis SpA, Covance |
| NCT00276952 | Phase 2 | Sep 1, 2004 | University of Chile |
Showing 4 of 4 trials
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Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Algenis SpA | For profit | 2 | 2 | 2 | 2015 |
| University of Chile | Academic/Hospital | 2 | 2 | 2 | 2004 |
| Covance | For profit | 1 | 0 | 1 | 2015 |
| Hospital San José | Academic/Hospital | 1 | 0 | 1 | 2019 |
4 organizations
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