gi-4000
Vaccineexperimental
Clinical trial activity
16 trials · 5 clinical orgs · 0 marketing orgs
Phase 1
10
Phase 2
15
Phase 3
0
Phase 4
0
Earliest trial started Jan 1, 2006 (NCT00300950)
Timeline
Indications
Studied for
- Breast Neoplasms · Phase 2
- Carcinoma, Hepatocellular · Phase 1/Phase 2
- Carcinoma, Non-Small-Cell Lung · Phase 2
- Carcinoma, Squamous Cell · Phase 1/Phase 2
- Carcinoma, Transitional Cell · Phase 1/Phase 2
- Colonic Neoplasms · Phase 2
- Colorectal Neoplasms · Phase 1/Phase 2
- Ovarian Neoplasms · Phase 1/Phase 2
- Pancreatic Neoplasms · Phase 2
- Triple Negative Breast Neoplasms · Phase 1/Phase 2
Mechanism of action
- Transforming protein p21/H-Ras-1Immunity, active
HRAS immunity, active
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- gi-4000
- gi-4000 vaccine
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03554109 | Phase 2 | Sep 30, 2018 | NantWorks |
| NCT03574649 | Phase 2 | Sep 30, 2018 | NantWorks |
| NCT03563144 | Phase 2 | Aug 31, 2018 | NantWorks |
| NCT03586869 | Phase 1/Phase 2 (Phase 2) | Jul 28, 2018 | NantWorks |
| NCT03563170 | Phase 1/Phase 2 (Phase 2) | May 25, 2018 | NantWorks |
| NCT03563157 | Phase 1/Phase 2 (Phase 2) | May 25, 2018 | NantWorks |
| NCT03387085 | Phase 1/Phase 2 (Phase 2) | Mar 16, 2018 | NantWorks |
| NCT03387111 | Phase 1/Phase 2 (Phase 2) | Jan 13, 2018 | NantWorks |
| NCT03387098 | Phase 1/Phase 2 (Phase 2) | Jan 2, 2018 | NantWorks |
| NCT03197571 | Phase 1/Phase 2 (Phase 2) | Dec 31, 2017 | NantWorks |
| NCT03197584 | Phase 1/Phase 2 (Phase 2) | Dec 31, 2017 | NantWorks |
| NCT03329248 | Phase 1/Phase 2 (Phase 2) | Nov 6, 2017 | NantWorks |
| NCT01322815 | Phase 2 | Oct 1, 2010 | Georgetown University, GlobeImmune |
| NCT00655161 | Phase 2 | Apr 1, 2008 | Cornell University, GlobeImmune |
| NCT00837135 | Phase 1 | Jan 1, 2008 | University of Pennsylvania |
| NCT00300950 | Phase 2 | Jan 1, 2006 | GlobeImmune |
Showing 16 of 16 trials
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Organizations
Research & Development (5)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| NantWorks | For profit | 12 | 12 | 1 | 2017 |
| GlobeImmune | For profit | 3 | 2 | 1 | 2006 |
| Cornell University | Academic/Hospital | 1 | 0 | 1 | 2008 |
| Georgetown University | Academic/Hospital | 1 | 1 | 1 | 2010 |
| University of Pennsylvania | Academic/Hospital | 1 | 1 | 1 | 2008 |
5 organizations
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