fontolizumab
mAbexperimental
Fontolizumab is a humanized monoclonal antibody and an immunosuppressive drug for the treatment of auto-immune diseases like Crohn's disease. A phase II clinical trial investigating the use for rheumatoid arthritis was terminated because the first phase did not meet the endpoint. — Wikipedia
Clinical trial activity
2 trials · 9 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
2
Phase 3
0
Phase 4
0
Earliest trial started Dec 1, 2005 (NCT00281294)
Timeline
2000s
- Jan 1, 2005
Earliest Phase 2 Sponsor(trial)
Indications
Mechanism of action
- Interferon gammaINHIBITOR
IFNG inhibitor
- Staphylococcus aureusImmunity, passive
Staphylococcus aureus immunity, passive
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaFontolizumab ↗
- ChEMBLCHEMBL2108459 ↗
Also known as
- asn100
- fontolizumab
- fontolizumab
- fontolizumab
- huzaf
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02940626 | Phase 2 | Nov 1, 2016 | Arsanis, Inc. |
| NCT00281294 | Phase 2 | Dec 1, 2005 | Altoona Center for Clinical Research, Coeur d Alene Arthritis Clinic, Denver Arthritis Clinic, Michigan State University, PDL BioPharma, Stanford University, Virginia Mason Medical Center, Wallace Rheumatic Study Center |
Showing 2 of 2 trials
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Organizations
Research & Development (9)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Altoona Center for Clinical Research | For profit | 1 | 0 | 1 | 2005 |
| Arsanis, Inc. | For profit | 1 | 1 | 1 | 2016 |
| Coeur d Alene Arthritis Clinic | Academic/Hospital | 1 | 0 | 1 | 2005 |
| Denver Arthritis Clinic | Academic/Hospital | 1 | 0 | 1 | 2005 |
| Michigan State University | Academic/Hospital | 1 | 0 | 1 | 2005 |
| PDL BioPharma | For profit | 1 | 1 | 1 | 2005 |
| Stanford University | Academic/Hospital | 1 | 0 | 1 | 2005 |
| Virginia Mason Medical Center | Academic/Hospital | 1 | 0 | 1 | 2005 |
| Wallace Rheumatic Study Center | Academic/Hospital | 1 | 0 | 1 | 2005 |
9 organizations
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