modithromycin

Small moleculeexperimental

Clinical trial activity

3 trials · 2 clinical orgs · 0 marketing orgs

Phase 1
2
Phase 2
1
Phase 3
0
Phase 4
0

Earliest trial started Dec 1, 2005 (NCT00270517)

Timeline

2000s

  1. Jan 1, 2005

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2008

    Earliest Phase 1 Sponsor(trial)

Indications

Mechanism of action

  • Unspecified targetUnclear

    unclear

Chemistry & pharmacology

Loading structure…

SMILES

CC[C@H]1OC(=O)[C@H](C)C(=O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@@]2(C)C[C@@H](C)/C(=N\C(C)=O)[C@H](C)[C@@H](OC/C(=N\OCc3ccc(-n4cccn4)nc3)CO2)[C@]1(C)O
Mol. weight
841.02 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • edp-322
  • edp420
  • edp 420
  • edp-420
  • edp-420
  • edp-420
  • ep-013420
  • modithromycin
  • s-013420

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT00989872Phase 1Oct 5, 2009Enanta Pharmaceuticals, PPD
NCT00990145Phase 1Nov 1, 2008Enanta Pharmaceuticals
NCT00270517Phase 2Dec 1, 2005Enanta Pharmaceuticals
Showing 3 of 3 trials
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Organizations

Research & Development (2)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Enanta PharmaceuticalsFor profit3322005
PPDFor profit1012009
2 organizations
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