gemeprost
Small moleculeexperimental
Gemeprost (16, 16-dimethyl-trans-delta2 PGE1 methyl ester) is an analogue of prostaglandin E1. — Wikipedia
Clinical trial activity
2 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Sep 1, 2011 (NCT01860521)
Timeline
2020s
- Jan 1, 2021
Earliest Phase 2 Sponsor(trial)
Indications
Mechanism of action
- Prostaglandin E synthaseSupplementation
PTGES supplementation
Chemistry & pharmacology
Loading structure…
SMILES
CCCCC(C)(C)[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCC/C=C/C(=O)OC- Mol. weight
- 394.55 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaGemeprost ↗
- ChEMBLCHEMBL1908315 ↗
Also known as
- 16,16-dimethyl-delta(2)-pge1 methyl ester
- 16,16-dimethyl-delta(2)-prostaglandin e1 methyl ester
- 16,16-dimethyl-trans-delta-2-pge1 methyl ester
- 16,16-dimethyl-trans-delta-2-pge1 methyl ester
- 16,16-dimethyl-trans-delta(2)-pge(1) methyl ester
- 16,16-dimethyl-trans-delta(2)-prostaglandin e(1) methyl ester
- 16,16-dimethyl-trans-delta(sup 2)-prostaglandin e1 methyl ester
- 16,16-dimethyl-trans-delta(sup 2)-prostaglandin e1 methyl ester
- 16,16-dmtdpgeme
- (2e,11 alpha,13e,15r)-11,15-dihydroxy-16,16- dimethyl-9-oxoprosta-2,13-dien-1-oic acid, methyl ester
- aventis brand of gemeprost
- carprost
- cergem
- cergem
- cervagem
- cervagem
- cervagem
- cervagem
- cervageme
- cervagème
- gemeprost
- gemeprost
- gemeprost
- gemeprost
- gemeprost
- gemeprost
- gemeprost
- gemeprost
- gemeprost, (2e,11alpha,13e,15r)-isomer
- nourypharm brand of gemeprost
- ono 802
- ono-802
- pg802
- sc-37681
- sc-37681
- sc-37681
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05342467 | Phase 2 | Nov 11, 2021 | National University of Malaysia |
| NCT01860521 | N/A | Sep 1, 2011 | University of Genoa |
Showing 2 of 2 trials
Page 1 / 1
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National University of Malaysia | Academic/Hospital | 1 | 1 | 1 | 2021 |
| University of Genoa | Academic/Hospital | 1 | 1 | 1 | 2011 |
2 organizations
Page 1 / 1