latiglutenase
Recombinant proteinexperimental
Clinical trial activity
10 trials · 14 clinical orgs · 0 marketing orgs
Phase 1
4
Phase 2
7
Phase 3
0
Phase 4
0
Earliest trial started Feb 1, 2008 (NCT00626184)
Timeline
Indications
Mechanism of action
- GlutenDEGRADER
Gluten degrader
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3137344 ↗
Also known as
- alv003
- alv003
- latiglutenase
- stan1
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04839575 | Phase 2 | Oct 31, 2021 | Immunogen, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Stanford University |
| NCT04243551 | Phase 2 | Feb 29, 2020 | Immunogen, Mayo Clinic, National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT03822208 | Phase 1 | Mar 29, 2019 | Alector Inc., Nucleus Network Ltd |
| NCT03585478 | Phase 2 | Jul 31, 2018 | Immunogen, Mayo Clinic, National Center for Complementary and Integrative Health (NCCIH), National Institutes of Health (NIH) |
| NCT01917630 | Phase 2 | Aug 1, 2013 | Alvine Pharmaceuticals Inc. |
| NCT01255696 | Phase 2 | Nov 1, 2010 | Alvine Pharmaceuticals Inc., FinnMedi Oy, University of Tampere |
| NCT00959114 | Phase 2 | Aug 1, 2009 | Alvine Pharmaceuticals Inc., FinnMedi Oy, University of Tampere |
| NCT00962182 | Phase 1/Phase 2 (Phase 2) | Aug 1, 2008 | Heim Pal Children's Hospital, Stanford University |
| NCT00669825 | Phase 1 | Mar 1, 2008 | Alvine Pharmaceuticals Inc. |
| NCT00626184 | Phase 1 | Feb 1, 2008 | Alvine Pharmaceuticals Inc., Clinical Applications Laboratories Inc. |
Showing 10 of 10 trials
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Organizations
Research & Development (14)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Alvine Pharmaceuticals Inc. | For profit | 5 | 5 | 2 | 2008 |
| Immunogen | For profit | 3 | 3 | 1 | 2018 |
| FinnMedi Oy | For profit | 2 | 0 | 1 | 2009 |
| Mayo Clinic | Academic/Hospital | 2 | 0 | 1 | 2018 |
| Stanford University | Academic/Hospital | 2 | 0 | 1 | 2008 |
| University of Tampere | Academic/Hospital | 2 | 0 | 1 | 2009 |
| Alector Inc. | For profit | 1 | 1 | 1 | 2019 |
| Clinical Applications Laboratories Inc. | For profit | 1 | 0 | 1 | 2008 |
| Heim Pal Children's Hospital | Academic/Hospital | 1 | 1 | 1 | 2008 |
| National Center for Complementary and Integrative Health (NCCIH) | Government | 1 | 0 | 1 | 2018 |
| National Institute of Allergy and Infectious Diseases (NIAID) | Government | 1 | 0 | 1 | 2020 |
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Government | 1 | 0 | 1 | 2021 |
| National Institutes of Health (NIH) | Government | 1 | 0 | 1 | 2018 |
| Nucleus Network Ltd | For profit | 1 | 0 | 1 | 2019 |
14 organizations
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