glycyrrhizin
Small moleculeexperimental
Glycyrrhizin is the chief sweet-tasting constituent of Glycyrrhiza glabra (liquorice) root. Structurally, it is a saponin used as an emulsifier and gel-forming agent in foodstuffs and cosmetics. Its aglycone is enoxolone. — Wikipedia
Clinical trial activity
14 trials · 20 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
6
Phase 3
4
Phase 4
3
Earliest trial started Mar 1, 2010 (NCT01342185)
Timeline
Indications
Approved for
Studied for
- Carcinoma · Phase 2
- Carcinoma, Hepatocellular · Phase 4
- Cervical Intraepithelial Neoplasia · Phase 4
- Drug Delivery Systems · Phase 2/Phase 3
- Esophageal Neoplasms · Phase 2
- Hepatitis B, Chronic · Phase 4
- Inflammation · Phase 4
- Neoplasms · Phase 2
- Neoplasms, Glandular and Epithelial · Phase 2
- Papillomavirus Infections · Phase 4
- Purpura, Thrombocytopenic, Idiopathic · Phase 2
- Squamous Intraepithelial Lesions · Phase 4
- Uterine Cervical Neoplasms · Phase 2
- Warts · Phase 3
Mechanism of action
- UnclearUnclear
Unclear unclear
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaGlycyrrhizin ↗
- ChEMBLCHEMBL4297742 ↗
Also known as
- diammonium glycyrrhizinate
- diammonium glycyrrhizinate
- glizigen
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05788705 | N/A | Jul 31, 2023 | Assiut University |
| NCT05916911 | Phase 4 | Jun 7, 2023 | Catalysis SL, Universidad Complutense de Madrid |
| NCT05276895 | N/A | Dec 1, 2022 | Assiut University |
| NCT06453304 | Phase 2/Phase 3 (Phase 3) | Mar 20, 2022 | Mansoura University |
| NCT05023915 | Phase 2 | Aug 21, 2021 | Shandong University |
| NCT04742660 | N/A | May 11, 2021 | Konkuk University |
| NCT03549273 | Phase 2 | Oct 1, 2018 | Catalysis SL |
| NCT04015245 | Phase 4 | Apr 12, 2018 | Chimei Medical Center |
| NCT03349008 | Phase 4 | Nov 25, 2017 | Jiangsu Chia-tai Tianqing Pharmaceutical Co.,Ltd |
| NCT03278444 | Phase 3 | Jul 18, 2017 | Anyang Regional Hospital, First People's Hospital of Shangqiu, Jiaozuo third people's hospital, Luoyang Central Hospital, Nanyang Central Hospital, Pingmei Shenma Medical Group General Hospital, Xinxiang Medical University, Zhengzhou University |
| NCT03584308 | Phase 2 | Oct 15, 2015 | Catalysis SL |
| NCT01643447 | N/A | May 1, 2012 | Eastern Hepatobiliary Surgery Hospital, People's Liberation Army of China |
| NCT01111344 | Phase 3 | Dec 1, 2010 | Catalysis SL |
| NCT01342185 | Phase 3 | Mar 1, 2010 | Southern Medical University, Tianyi medical instruments limited company |
Showing 14 of 14 trials
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Organizations
Research & Development (20)
20 organizations
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