tagatose

Small moleculeexperimental

Tagatose is a hexose monosaccharide. It is found in small quantities in a variety of foods, and has attracted attention as an alternative sweetener. It is often found in dairy products, because it is formed when milk is heated. It is similar in texture and appearance to sucrose :215 and is 92% as sweet,:198 but with only 38% of the calories.:209 Tagatose is generally recognized as safe by the Food and Agriculture Organization and the World Health Organization, and has been since 2001. Since it is metabolized differently from sucrose, tagatose has a minimal effect on blood glucose and insulin levels. Tagatose is also approved as a tooth-friendly ingredient for dental products. Consumption of more than about 30 grams of tagatose in a dose may cause gastric disturbance in some people, as it is mostly processed in the large intestine, similar to soluble fiber.:214 — Wikipedia

Clinical trial activity

4 trials · 6 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
2
Phase 3
1
Phase 4
0

Earliest trial started Apr 1, 2007 (NCT00955747)

Timeline

2000s

  1. Jan 1, 2007

    Earliest Phase 3 Sponsor(trial)

  2. Jan 1, 2008

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

  • Unspecified targetUnclear

    Unclear

Chemistry & pharmacology

Loading structure…

SMILES

O=C(CO)[C@@H](O)[C@@H](O)[C@H](O)CO
Mol. weight
180.16 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • d-lyxo-hex-2-ulose
  • d-lyxo-hex-2-ulose
  • d-lyxo-hexulose
  • d-lyxo-hexulose
  • d-tag
  • d-tag
  • d-tagatose
  • d-tagatose
  • d-tagatose
  • d-tagatose
  • tagatose
  • tagatose
  • tagatose
  • tagatose
  • tagatose, (alpha-d)-isomer
  • tagatose, (beta-d)-isomer
  • tagatose, (d)-isomer
  • tagatose, (dl)-isomer

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06230900N/AFeb 5, 2024Gelderse Vallei Hospital, TNO, Wageningen University
NCT04327245N/AJan 15, 2017University of Chile
NCT00961662Phase 2Feb 1, 2008Spherix Incorporated, University of Kentucky
NCT00955747Phase 3Apr 1, 2007Spherix Incorporated, University of Kentucky
Showing 4 of 4 trials
Page 1 / 1

Organizations

Research & Development (6)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Spherix IncorporatedFor profit2222007
University of KentuckyAcademic/Hospital2022007
Gelderse Vallei HospitalAcademic/Hospital1012024
TNOFor profit1012024
University of ChileAcademic/Hospital1112017
Wageningen UniversityAcademic/Hospital1112024
6 organizations
Page 1 / 1