cremophor
Kolliphor EL, formerly known as Cremophor EL, is the registered trademark of BASF Corp. for its version of polyethoxylated castor oil. It is prepared by reacting 35 moles of ethylene oxide with each mole of castor oil. The resulting product is a mixture : the major component is the material in which the hydroxyl groups of the castor oil triglyceride have been ethoxylated with ethylene oxide to form polyethylene glycol ethers. Minor components are the polyethyelene glycol esters of ricinoleic acid, polyethylene glycols and polyethylene glycol ethers of glycerol. Kolliphor EL is a synthetic, nonionic surfactant used to stabilize emulsions of nonpolar materials in water. — Wikipedia
Clinical trial activity
1 trials · 4 clinical orgs · 0 marketing orgs
Earliest trial started Jan 1, 2012 (NCT01489826)
Timeline
2010s
- Jan 1, 2012
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
Mechanism of action
- excipientOTHER
excipient other
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaKolliphor EL ↗
Also known as
- chremofore
- cremophor
- cremophor
- cremophor
- cremophor ap
- cremophor, o(beta)-isomer
- cremophor rh 40
- cremophor rh 40-60
- cremophor wo-ce 5070
- macrogloglycerol hydrostearate 40
- mgh 40
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01489826 | Phase 1 | Jan 1, 2012 | e-Therapeutics PLC, Newcastle University, The Beatson West of Scotland Cancer Centre, University of Leeds |
Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| e-Therapeutics PLC | For profit | 1 | 1 | 1 | 2012 |
| Newcastle University | Academic/Hospital | 1 | 0 | 1 | 2012 |
| The Beatson West of Scotland Cancer Centre | Academic/Hospital | 1 | 0 | 1 | 2012 |
| University of Leeds | Academic/Hospital | 1 | 0 | 1 | 2012 |