d-ribose
Ribose is a simple sugar and carbohydrate with molecular formula C5H10O5 and the linear-form composition H−(C=O)−(CHOH)4−H. The naturally occurring form, d-ribose, is a component of the ribonucleotides from which RNA is built, and so this compound is necessary for coding, decoding, regulation and expression of genes. It has a structural analog, deoxyribose, which is a similarly essential component of DNA. l-ribose is an unnatural sugar that was first prepared by Emil Fischer and Oscar Piloty in 1891. It was not until 1909 that Phoebus Levene and Walter Jacobs recognised that d-ribose was a natural product, the enantiomer of Fischer and Piloty's product, and an essential component of nucleic acids. Fischer chose the name "ribose" as it is a partial rearrangement of the name of another sugar, arabinose, of which ribose is an epimer at the 2' carbon; both names also relate to gum arabic, from which arabinose was first isolated and from which they prepared l-ribose. — Wikipedia
Clinical trial activity
11 trials · 22 clinical orgs · 0 marketing orgs
Earliest trial started Mar 1, 1995 (NCT00004658)
Timeline
1990s
- Jan 1, 1995
Earliest Phase 2 Sponsor(trial)
Indications
Mechanism of action
- Unspecified targetSupplementation
supplementation
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaRibose ↗
Also known as
- d-ribose
- d-ribose
- ribose
- ribose
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03133793 | Phase 2 | Nov 1, 2017 | University of Kansas |
| NCT03411369 | N/A | Jun 1, 2016 | University of Pavia |
| NCT02260141 | Phase 2 | Sep 1, 2014 | Practitioners Alliance Network |
| NCT01858480 | Phase 2 | Jul 1, 2013 | Boston University, RiboCor, Inc. |
| NCT01727479 | N/A | Aug 31, 2012 | Atrium Innovations, Laval University |
| NCT01315210 | Phase 2 | May 1, 2011 | RiboCor, Inc., University of Kentucky |
| NCT01108549 | N/A | Apr 1, 2009 | Bioenergy Life Science, Inc., Integrative Therapeutics, Inc., Kona Research Center |
| NCT00821067 | N/A | Jan 1, 2009 | Bioenergy Life Science, Inc. |
| NCT00566514 | N/A | Jul 1, 2006 | Bioenergy Life Science, Inc., The Annapolis Center for Effective CFS/Fibromyalgia Therapies |
| NCT00329485 | N/A | Jun 1, 2006 | Department of Veteran Affairs, Maine Research Associates, Ohio State University, Scottsdale Cardiovascular Research Institute, Texas Heart Institute, University of Florida, University of Utah, Valen Labs |
| NCT00004658 | Phase 2 | Mar 1, 1995 | National Center for Research Resources (NCRR), University of California, San Diego |