chlorogenic acid
Small moleculeexperimental
Chlorogenic acid (CGA) is the ester of caffeic acid and quinic acid, functioning as an intermediate in lignin biosynthesis. — Wikipedia
Clinical trial activity
11 trials · 12 clinical orgs · 0 marketing orgs
Phase 1
4
Phase 2
2
Phase 3
2
Phase 4
0
Earliest trial started May 1, 2014 (NCT02136342)
Timeline
Indications
Mechanism of action
- Cell membraneDISRUPTING AGENT
Cell membrane disrupting agent
Chemistry & pharmacology
Loading structure…
SMILES
O=C(/C=C/c1ccc(O)c(O)c1)O[C@@H]1C[C@](O)(C(=O)O)C[C@@H](O)[C@H]1O- Mol. weight
- 354.31 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaChlorogenic acid ↗
- ChEMBLCHEMBL284616 ↗
Also known as
- chlorogenic acid
- chlorogenic acid
- chlorogenic acid
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03758014 | Phase 2/Phase 3 (Phase 3) | Nov 27, 2018 | Capital Medical University, Sichuan J.Z. Bio-chemical Science and Technology Development Co., Ltd |
| NCT03751592 | Phase 1/Phase 2 (Phase 2) | Jul 17, 2018 | Chinese Academy of Medical Sciences, Sichuan J.Z. Bio-chemical Science and Technology Development Co., Ltd |
| NCT03444558 | N/A | Jun 1, 2017 | University of Catania, University of Palermo |
| NCT03019263 | N/A | Mar 31, 2017 | University of Pavia |
| NCT02929901 | Phase 2/Phase 3 (Phase 3) | Dec 1, 2016 | National Nutrition and Food Technology Institute |
| NCT02887950 | N/A | Sep 1, 2016 | Leonardo Medica Srl, University of Pavia |
| NCT02728349 | Phase 1 | Feb 1, 2016 | Capital Medical University, Sichuan J.Z. Bio-chemical Science and Technology Development Co., Ltd |
| NCT02524938 | N/A | Oct 1, 2015 | University of Glasgow |
| NCT02621060 | Phase 2 | Sep 1, 2015 | University of Guadalajara |
| NCT02245204 | Phase 1 | Sep 1, 2014 | Peking University, Sichuan J.Z. Bio-chemical Science and Technology Development Co., Ltd, Soochow University |
| NCT02136342 | Phase 1 | May 1, 2014 | Chinese Academy of Medical Sciences, Sichuan J.Z. Bio-chemical Science and Technology Development Co., Ltd |
Showing 11 of 11 trials
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Organizations
Research & Development (12)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Sichuan J.Z. Bio-chemical Science and Technology Development Co., Ltd | For profit | 5 | 4 | 3 | 2014 |
| Capital Medical University | Academic/Hospital | 2 | 0 | 2 | 2016 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 2 | 1 | 2 | 2014 |
| University of Pavia | Academic/Hospital | 2 | 2 | 1 | 2016 |
| Leonardo Medica Srl | For profit | 1 | 0 | 1 | 2016 |
| National Nutrition and Food Technology Institute | Government | 1 | 1 | 1 | 2016 |
| Peking University | Academic/Hospital | 1 | 0 | 1 | 2014 |
| Soochow University | Academic/Hospital | 1 | 0 | 1 | 2014 |
| University of Catania | Academic/Hospital | 1 | 0 | 1 | 2017 |
| University of Glasgow | Academic/Hospital | 1 | 1 | 1 | 2015 |
| University of Guadalajara | Academic/Hospital | 1 | 1 | 1 | 2015 |
| University of Palermo | Academic/Hospital | 1 | 1 | 1 | 2017 |
12 organizations
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